Results 71 to 80 of about 168,896 (284)

Systematic Evaluation of Data and Trial Fitness for Oncology Trial Emulation: Empirical Findings from the CARE Initiative

open access: yesClinical Pharmacology &Therapeutics, EarlyView.
The Coalition to Advance Real‐World Evidence through Randomized Controlled Trial Emulation (CARE) Initiative seeks to advance understanding of when real‐world data (RWD) can generate valid treatment effectiveness estimates by emulating completed oncology randomized controlled trials (RCTs).
Natalie Levy   +42 more
wiley   +1 more source

Robinow syndrome DVL1 variants disrupt morphogenesis and appendage formation in a Drosophila disease model

open access: yesDevelopmental Dynamics, EarlyView.
Abstract Background Robinow syndrome is a rare developmental syndrome caused by variants in genes in Wnt signaling pathways. We previously showed that expression of patient variants in Dishevelled 1 (DVL1) in Drosophila and chicken models disrupts the balance of canonical and non‐canonical Wnt signaling.
Gamze Akarsu   +4 more
wiley   +1 more source

Joyce Gilbert

open access: yes, 1955
Infant's school, McMinn Street.

core  

The role of Rho GTPases in facial morphogenesis

open access: yesDevelopmental Dynamics, EarlyView.
The role of small GTPases, RHOA, RAC1, and CDC42 and pathway mediators is reviewed in the context of embryonic facial development. Lip fusion requires cytoskeletal remodeling during morphogenesis of the facial processes and during lip fusion. Fnm, frontonasal mass; lnp, lateral nasal process; mnp, medial nasal process; mxp, maxillary process; np, nasal
Isra Ibrahim, Joy M. Richman
wiley   +1 more source

Prevalence of transthyretin cardiac amyloidosis in undifferentiated heart failure with preserved ejection fraction

open access: yesESC Heart Failure, Volume 12, Issue 2, Page 1176-1182, April 2025.
Abstract Aims Transthyretin amyloid cardiomyopathy (ATTR‐CM) is an increasinglyrecognized cause of heart failure with preserved ejection fraction (HFpEF), which may be diagnosed non‐invasively using 99mTc 3,3‐diphosphono‐1,2‐propanodicarboxylic acid (DPD) scintigraphy‐based diagnostic criteria.
L. Healy   +15 more
wiley   +1 more source

Continuing professional development for primary care physicians: a pre-post analysis of a focused abdominal point-of-care ultrasound pilot training

open access: yesBMC Medical Education
Introduction Abdominal pain is a leading cause of primary care visits and emergency department admissions. The recent surge in the implementation of point-of-care ultrasound into primary care underscores the necessity for specialized training to enhance ...
Itamar Ben Shitrit   +9 more
doaj   +1 more source

Maternal and umbilical cord plasma concentrations of antiseizure medications: Results from the observational MONEAD study

open access: yesEpilepsia, EarlyView.
Abstract Objective Unanticipated changes in antiseizure medication (ASM) exposure can lead to subtherapeutic or toxic medication concentrations in the mother and unnecessary drug exposure for the fetus. The objectives of this study were to characterize ASM concentrations in mother's and cord blood at delivery in women with epilepsy (PWWE).
Charul Avachat   +138 more
wiley   +1 more source

Partitive restrictive modification of names in English: Arguments for their metonymic motivation

open access: yesQuaderns de Filologia: Estudis Lingüístics, 2014
La finalidad del trabajo es la de presentar argumentos en favor de la tesis de la motivación metonímica de la construcción llamada por Quirk et al. “modificación restrictiva partitiva” (como en The young Joyce was already a great writer), en la que un ...
Antonio Barcelona Sánchez
doaj   +1 more source

Joyce Gilbert

open access: yes, 1968
Mangiwa, Therese, Padinta, Galuma, Shirley Stagg, Nanette Bird, Preschool teaching assistants.

core  

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