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Design and Pictet–Spengler enabled synthesis of carboxamide-substituted imidazo[1,2-a]quinoxalines as dual EGFR and tubulin targeting anticancer agents [PDF]
Journal of Enzyme Inhibition and Medicinal ChemistryIn this study, we report the Pictet–Spengler enabled synthesis of a series of eighteen carboxamide-substituted imidazo[1,2-a]quinoxaline derivatives (JRC-1-JRC-18) targeting epidermal growth factor receptor (EGFR) and tubulin.
Joydeep Chatterjee +8 more
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Expression and Analysis of Scale Effect and Anisotropy of Joint Roughness Coefficient Values Using Confidence Neutrosophic Number Cubic Values [PDF]
Neutrosophic Sets and Systems, 2023 : The JRC data collected from a rock mass joint surface difficultly obtain enough large-scale JRC sample data, but small-scale JRC sample data, which usually contain indeterminate and incomplete information due to the limitation of the measurement ...
Zhenhan Zhang, Jun Ye
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Direct Shear Test and Shear Strength Model of Clay-Filled Joints
Applied Rheology, 2021 To better study the shear characteristics of infilled joints with soil having different moisture contents, the influence of the moisture content on the shear characteristics of the infilled joint was explored in this paper, and a revised shear strength ...
Chang Le +3 more
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Advances in joint roughness coefficient (JRC) and its engineering applications
Journal of Rock Mechanics and Geotechnical Engineering, 2023 The joint roughness coefficient (JRC), introduced in Barton (1973) represented a new method in rock mechanics and rock engineering to deal with problems related to joint roughness and shear strength estimation.
Nick Barton, Changshuo Wang, Rui Yong
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Paradigm Shift in Studying Joint Micro-Roughness Coefficients using Graph Theory [PDF]
International Journal of Mining and Geo-Engineering, 2019 In this paper, the ranking of joint roughness coefficients (JRC) profiles as well-known acceptable pattern for studying rough surfaces are investigated.
Mohammad Lotfi, Behzad Tokhmechi
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Joint Radar and Communications Waveform Design Based on Complementary Sequence Sets
Remote Sensing, 2023 The joint radar and communications (JRC) waveform often has a high range sidelobe, which will degrade the target detection performance of an automotive JRC system.
Haichuan Li +3 more
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Machine learning-based optimization of photogrammetric JRC accuracy
Scientific ReportsTo improve the accuracy of photogrammetric joint roughness coefficient (JRC) estimation, this study proposes two optimization models based on ground sample distance (GSD), point density, and the root mean square error (RMSE) of checkpoints.
Qinzheng Yang +5 more
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Advances in Civil Engineering, 2021 The 10 standard roughness joint profiles provided a visual comparison to get the joint roughness coefficient (JRC) of rock joint surface, but the accuracy of this method is influenced by human factors.
Zhiqiang Zhang +3 more
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The JRC multidisciplinary research data infrastructure [PDF]
Proceedings of the 19th International Conference on Information Integration and Web-based Applications & Services, 2017 This paper presents the approach adopted by the European Commission's Joint Research Centre (JRC) in order to facilitate open access to its research data crated as support for EU policies, which is also in line with the general Open Data trend.
Anders Friis-Christensen +3 more
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Applied Rheology, 2023 Roughness and inclination are important factors affecting the strength and deformation properties of jointed rock masses. Serrated joint specimens with varying joint roughness coefficient (JRC) and inclination angle were manufactured by 3D printing ...
Yuan Pu +3 more
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