Results 11 to 20 of about 410,863 (259)
Intratumour heterogeneity complicates precision management of advanced endometrial cancer. Circulating tumor DNA (ctDNA) offers a minimally invasive strategy to capture tumor evolution and therapeutic resistance. Here, we compare tumor‐agnostic NGS with tumor‐informed ddPCR, outlining their relative sensitivity, concordance, and clinical implications ...
Carlos Casas‐Arozamena +15 more
wiley +1 more source
We identify USP29 as the only DUB mirroring CA9 expression, a marker of hypoxia and HIF pathway activation associated with PCA aggressiveness. USP29 stabilizes HIF‐1α and HIF‐2α via a noncanonical mechanism that is independent of PHD/pVHL activity yet relies on proteasomal regulation, establishing USP29 as a previously unrecognized regulator of hypoxic
Amelie S Schober +16 more
wiley +1 more source
BİR İDEAL OLARAK DON JUAN Baştan Çıkarıcının Duyumsal-Müzikali
Don Juan is a myth that many of us know very well. The common interpretation of this myth is that Don Juan is a lecherous or indecent man who deceived young girls with the promise of marriage.
Senem KURTAR
doaj +1 more source
Cracking the Code: Genotype–Phenotype Correlation Models in Sarcoglycanopathies
ABSTRACT Objective Sarcoglycanopathies are among the most severe limb‐girdle muscular dystrophies (LGMD), though milder presentations have been described. These diseases are primarily caused by missense variants, but the limited predictability of their effect on protein maturation, complex formation, and transport has hindered reliable genotype ...
Leonela Luce +72 more
wiley +1 more source
New record of Boa constrictor occidentalis Philippi, 1873 (Serpentes: Boidae) in San Juan province, Argentina [PDF]
We document the first record of Boa constrictor in Valle Fértil department, San Juan province, Argentina. The specimen was collected and deposited in the herpetological collection of the Department of Biology, Universidad Nacional San Juan.
Tomás Martínez +3 more
doaj +3 more sources
Predictive Ability of Plasma p‐tau217 for β‐Amyloid Status: A Prospective Multicenter Study
ABSTRACT Objective Plasma tau phosphorylated at threonine 217 (p‐tau217) measured with fully automated platforms has shown high accuracy for Alzheimer's disease (AD) diagnosis, but real‐world multicenter data remain limited. We aimed to validate the diagnostic performance of p‐tau217 for identifying AD pathology in a real‐world multicenter cohort ...
Miquel Massons +33 more
wiley +1 more source
ABSTRACT Introduction/Objective Acute intracranial stenting during endovascular thrombectomy (EVT) for ischemic stroke requires intraprocedural antiplatelet therapy (APT) to maintain patency. However, the hemorrhagic risk of combining APT with intravenous thrombolysis (IVT) remains uncertain.
Aaron Rodriguez‐Calienes +75 more
wiley +1 more source
El contexto litúrgico como clave hermenéutica eclesial del evangelio según San Juan
El autor propone tener en cuenta el contexto litúrgico en el que se proclaman y comentan las perícopas joánicas como clave hermenéutica necesaria para la actualización del texto bíblico.
Jordi Latorre Castillo, SDB
doaj
Deep Learning Pose Estimation for Phenotyping of Co‐Occurring Hyperkinetic Movement Disorders
ABSTRACT Objective To explore whether routine outpatient video combined with deep learning‐based pose estimation and clinically interpretable kinematic features can support multi‐label phenotyping of co‐occurring hyperkinetic movement disorders (HMDs).
Laura Cif +17 more
wiley +1 more source
El milagro de la resurrección de Lázaro por parte de Jesús se encuentra en el evangelio de Juan. A la hora de estudiarlo, tanto el exegeta como el lector deben concentrar toda su atención en no perder ninguno de los rasgos que de sí revela Jesús en este ...
José María Bover Oliver
doaj

