Results 11 to 20 of about 1,864,506 (308)

Innovación en el sector agropecuario de San Juan : resultados de 8 proyectos de investigación y extensión [PDF]

open access: yes, 2022
En el año 2018, el Instituto Nacional de Tecnología Agropecuaria (INTA) a nivel nacional planteó la necesidad de reformular la cartera programática de la institución. El Centro Regional (CR) Mendoza–San Juan de INTA propuso una metodología innovadora en

core  

Longitudinal circulating tumor DNA profiling in patients with advanced endometrial cancer using an off‐the‐shelf targeted NGS panel

open access: yesMolecular Oncology, EarlyView.
Intratumour heterogeneity complicates precision management of advanced endometrial cancer. Circulating tumor DNA (ctDNA) offers a minimally invasive strategy to capture tumor evolution and therapeutic resistance. Here, we compare tumor‐agnostic NGS with tumor‐informed ddPCR, outlining their relative sensitivity, concordance, and clinical implications ...
Carlos Casas‐Arozamena   +15 more
wiley   +1 more source

USP29‐regulated noncanonical stabilization of the hypoxia‐inducible factor‐α in aggressive prostate cancer

open access: yesMolecular Oncology, EarlyView.
We identify USP29 as the only DUB mirroring CA9 expression, a marker of hypoxia and HIF pathway activation associated with PCA aggressiveness. USP29 stabilizes HIF‐1α and HIF‐2α via a noncanonical mechanism that is independent of PHD/pVHL activity yet relies on proteasomal regulation, establishing USP29 as a previously unrecognized regulator of hypoxic
Amelie S Schober   +16 more
wiley   +1 more source

The Juan non-LTR retrotransposon in mosquitoes: genomic impact, vertical transmission and indications of recent and widespread activity

open access: yesBMC Evolutionary Biology, 2007
Background In contrast to DNA-mediated transposable elements (TEs), retrotransposons, particularly non-long terminal repeat retrotransposons (non-LTRs), are generally considered to have a much lower propensity towards horizontal transfer.
Tu Zhijian, Biedler James K
doaj   +1 more source

Cracking the Code: Genotype–Phenotype Correlation Models in Sarcoglycanopathies

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Sarcoglycanopathies are among the most severe limb‐girdle muscular dystrophies (LGMD), though milder presentations have been described. These diseases are primarily caused by missense variants, but the limited predictability of their effect on protein maturation, complex formation, and transport has hindered reliable genotype ...
Leonela Luce   +72 more
wiley   +1 more source

New record of Boa constrictor occidentalis Philippi, 1873 (Serpentes: Boidae) in San Juan province, Argentina [PDF]

open access: yesCheck List, 2015
We document the first record of Boa constrictor in Valle Fértil department, San Juan province, Argentina. The specimen was collected and deposited in the herpetological collection of the Department of Biology, Universidad Nacional San Juan.
Tomás Martínez   +3 more
doaj   +3 more sources

Religião e ficção na narrativa de Juan Rulfo [PDF]

open access: yes, 2001
Tese (doutorado) - Universidade Federal de Santa Catarina, Centro de Comunicação e Expressão. Curso de Pós-Graduação em LiteraturaOs personagens que povoam a narrativa de Juan Rulfo, vivem, falam e rezam como os habitantes do centro ocidental do México,
Camorlinga Alcaraz, Rafael
core  

Predictive Ability of Plasma p‐tau217 for β‐Amyloid Status: A Prospective Multicenter Study

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Plasma tau phosphorylated at threonine 217 (p‐tau217) measured with fully automated platforms has shown high accuracy for Alzheimer's disease (AD) diagnosis, but real‐world multicenter data remain limited. We aimed to validate the diagnostic performance of p‐tau217 for identifying AD pathology in a real‐world multicenter cohort ...
Miquel Massons   +33 more
wiley   +1 more source

La muerte y la niña de Juan Carlos Onetti: a tensão morte-origem [PDF]

open access: yes, 2014
Dissertação (mestrado) - Universidade Federal de Santa Catarina, Centro de Comunicação e Expressão, Programa de Pós-Graduação em Literatura, Florianópolis, 2014.Este trabalho versa sobre a tensão entre a morte e a origem na nouvelle La muerte y la niña ...
Terenzi, Juan Manuel
core  

Interaction of Intraprocedural Antiplatelets and Intravenous Thrombolysis in Acute Intracranial Stenting: RESISTANT Registry Subanalysis

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Introduction/Objective Acute intracranial stenting during endovascular thrombectomy (EVT) for ischemic stroke requires intraprocedural antiplatelet therapy (APT) to maintain patency. However, the hemorrhagic risk of combining APT with intravenous thrombolysis (IVT) remains uncertain.
Aaron Rodriguez‐Calienes   +75 more
wiley   +1 more source

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