Results 161 to 170 of about 62,905 (262)

The effect of mild and moderate hepatic impairment on the pharmacokinetics, safety and tolerability of balcinrenone

British Journal of Clinical Pharmacology, EarlyView.
Abstract Aim Balcinrenone (previously AZD9977) is a novel selective non‐steroidal mineralocorticoid receptor antagonist (MRA) with a differential mechanism of action relative to approved MRAs. The aim of this trial was to assess the pharmacokinetics, safety and tolerability of balcinrenone in participants with mild and moderate hepatic impairment ...
Anna L. Eriksson, Deeyen Karsanji, Bonifride Tuyishimire, Joanna Parkinson, Maria Heijer, Tadeusz Pawlik, Judith Hartleib‐Geschwindner, Maria Leonsson‐Zachrisson, Hans Ericsson   +8 more
wiley   +1 more source

[Integrated care for long-responder women with metastatic breast cancer: Expert opinion for long term management in spain]. [PDF]

Aten Primaria
González V, Martínez Martínez MT, Sanmartín A, de la Haba-Rodríguez JR, Martínez Denaro D, López A.   +5 more
europepmc   +1 more source

Implementation and use of risk minimization control tools in the EU: A multistakeholder survey

British Journal of Clinical Pharmacology, EarlyView.
Aims This study characterized stakeholders' experiences with national implementation of risk minimization control tools (RMCTs), such as healthcare professional qualification, healthcare facility accreditation and medical intervention prior to treatment initiation, for eight medicinal products across eight European Union countries. Methods We conducted
Sharon C. M. Essink, Iris R. Joosse, Maximilian Salcher‐Konrad, Melanie Walter, Elena Deligianni, Dimitra Tsioumela, Christos Kontogiorgis, Elita Poplavska, Iluta Žīgure, Christina E. Hoeve, Teresa Leonardo Alves, Ella D. van Vliet, Renato Ferreira‐da‐Silva, Ana Kodrič, Mitja Kos, Juan Erviti, Marta Gutiérrez‐Valencia, Luis Carlos Saiz, Sofia Kälvemark Sporrong, Emelie Karlsson, Christine Leopold, Marie L. De Bruin   +21 more
wiley   +1 more source

Sit-to-stand test as a complementary assessment in patients with cardiovascular disease. [PDF]

Rev Cuid
Avila-Valencia JC, Betancourt-Peña J, Saavedra-Orozco NA, Benavides-Cordoba V.   +3 more
europepmc   +1 more source

Echocardiographic characterization and markers of cardiovascular risk in adults with sickle cell disease in a Colombian tertiary referral centre: A cross-sectional study. [PDF]

PLoS One
Arrieta-Mendoza ME, Betancourt JR, Ayala-Zapata S, Barbosa-Balaguera S, Messu-Llanos CD, Rosales-Melo JP, Andrade-Hoyos DF, Herrera-Escandón Á, Aguilar-Molina OE.   +8 more
europepmc   +1 more source

Real‐Time Biomass Estimation in High‐Density Yeast Fermentations Using Soft Sensor Modeling

Biotechnology and Bioengineering, EarlyView.
Accurate biomass measurements, both offline and online, are essential to improve prediction and control in yeast fermentation. This study develops regression‐based predictive models to correlate offline measurements (Dry Cell Weight and OD600 from a spectrophotometer) with online OD860 probe signals to provide accurate real‐time biomass estimations and
Ana G. Del Hierro, José Luis Checa‐Barrera, Juan A. Moreno‐Cid, Eoin Casey   +3 more
wiley   +1 more source

Beyond Surveillance Mutations: Long-Term Trends and Clinical Relevance of Transmitted HIV Drug Resistance in Spain (2007-2023). [PDF]

Open Forum Infect Dis
Muñoz Báez P, Illescas López M, de Salazar A, Falces Romero I, Pinto A, Portilla I, Masiá M, Peraire J, Alemán Valls MR, Sanchiz M, Iborra A, Baza B, Aguilera A, Olalla J, Espinosa N, Iribarren JA, Gisbert L, Imaz A, Montero M, Navarro Marcotegui M, Suárez-García I, Riera M, Pérez Elias MJ, Galán JC, García Fraile LJ, Sanz J, Ibarra Ugarte S, Bernal E, Blanco JR, Navarro G, Martínez O, Viciana Ramos MI, Mohamen-Balghata MO, Delgado E, Thompson MM, Moreno C, CoRIS C, Fuentes A, García F.   +38 more
europepmc   +1 more source

How wildlife respond to tropical cyclones: short‐term tactics and long‐term impacts

Biological Reviews, EarlyView.
ABSTRACT From butterflies to lizards and from sharks to seabirds, wildlife exhibit tactics to survive the impacts of tropical cyclones, also known as hurricanes, cyclones, or typhoons depending on where they occur. Some species seek refuge during the storm by moving, some remain in place and ride it out, and others move longer distances, avoiding the ...
Erin L. Koen, Mohamed Khalil Meliane, Zachery B. Holmes, Karl E. Miller, William J. Barichivich, Emilie Dedeban, Alex Furst, Miranda Imeri, Peyton E. Niebanck, Samantha Nunn, Kailee Pearson, Nicole Rita, Brier Ryver, Dakotah Shaffer, Susan C. Walls, E. Hance Ellington   +15 more
wiley   +1 more source

Hypercapnia as a Key Mechanism in the Development of Pulmonary Hypertension in Malignant Pertussis: A Case Report. [PDF]

Respirol Case Rep
Muñoz-Bonet JI, Sebastián-Cuevas FJ, Flor-Macián EM, Ortega-Sánchez MDC, Rodríguez-Sacristán A, Brines J.   +5 more
europepmc   +1 more source