Results 21 to 30 of about 62,006 (260)
ComputersShadows in remote sensing images often introduce challenges in accurate segmentation due to their variability in shape, size, and texture. To address these issues, this study proposes the Supervised Dynamic Kernel U-Net (SDKU-Net), a novel architecture ...
Gilberto Alvarado-Robles +3 more
doaj +1 more source
Molecular Oncology, EarlyView.We identify USP29 as the only DUB mirroring CA9 expression, a marker of hypoxia and HIF pathway activation associated with PCA aggressiveness. USP29 stabilizes HIF‐1α and HIF‐2α via a noncanonical mechanism that is independent of PHD/pVHL activity yet relies on proteasomal regulation, establishing USP29 as a previously unrecognized regulator of hypoxic
Amelie S Schober +16 more
wiley +1 more source
Cracking the Code: Genotype–Phenotype Correlation Models in Sarcoglycanopathies
Annals of Clinical and Translational Neurology, EarlyView.ABSTRACT Objective Sarcoglycanopathies are among the most severe limb‐girdle muscular dystrophies (LGMD), though milder presentations have been described. These diseases are primarily caused by missense variants, but the limited predictability of their effect on protein maturation, complex formation, and transport has hindered reliable genotype ...
Leonela Luce +72 more
wiley +1 more source
Predictive Ability of Plasma p‐tau217 for β‐Amyloid Status: A Prospective Multicenter Study
Annals of Clinical and Translational Neurology, EarlyView.ABSTRACT Objective Plasma tau phosphorylated at threonine 217 (p‐tau217) measured with fully automated platforms has shown high accuracy for Alzheimer's disease (AD) diagnosis, but real‐world multicenter data remain limited. We aimed to validate the diagnostic performance of p‐tau217 for identifying AD pathology in a real‐world multicenter cohort ...
Miquel Massons +33 more
wiley +1 more source
Annals of Clinical and Translational Neurology, EarlyView.ABSTRACT Introduction/Objective Acute intracranial stenting during endovascular thrombectomy (EVT) for ischemic stroke requires intraprocedural antiplatelet therapy (APT) to maintain patency. However, the hemorrhagic risk of combining APT with intravenous thrombolysis (IVT) remains uncertain.
Aaron Rodriguez‐Calienes +75 more
wiley +1 more source
Revista Científica Ciencias de la SaludIntroducción. La adolescencia es un periodo de desarrollo biopsicosocial que va desde los 10 a 19 años, el embarazo entre estas edades supone una preocupación para la salud pública por todo lo que conlleva. Objetivo.
Samuel Guarnieri Granero +5 more
doaj +1 more source
Arthritis Care &Research, EarlyView.Objective JAK inhibitors (JAKi) have shown promising effects in early‐phase studies of systemic sclerosis (SSc). We aimed to assess the safety and explore the effectiveness of JAKi compared to conventional immunosuppressants in SSc. Methods A longitudinal retrospective study of the European Scleroderma Trials and Research Group (EUSTAR) cohort was ...
Stefano Di Donato +27 more
wiley +1 more source
Advanced Functional Materials, EarlyView.A graded‐interface hydrogel‐polymer electrolyte decouples water activity to simultaneously stabilize the Zn anode and sustain cathode kinetics. The flexible design supports dendrite‐free cycling over 1600 h, high capacity in both MnO2 and V2O5 full cells, and stable pouch‐cell performance under bending, resolving the fundamental water conflict in ...
Shuyun Wang +8 more
wiley +1 more source
A Two-Stage Twisted Blade μ-Vertical Axis Wind Turbine: An Enhanced Savonius Rotor Design
EnergiesWind turbines are a solution for sustainable energy, significantly reducing carbon emissions and fostering a circular economy for more cost-effective and cleaner power generation, in line with worldwide environmental aspirations.
Andrés Pérez-Terrazo +3 more
doaj +1 more source
Lesiones Pre-Cancerosas del Cuello Uterino: Correlación Colposcopica, Citológica e Histológica.
Revista Colombiana de Obstetricia y Ginecología, 1972 Ha sido y sigue siendo motivo de gran preocupación el significado de ciertas lesiones cervicales, cuyas características celulares las han catalogado en precancerosas del epitelio cervical, porque muchas veces se les encuentran asociadas al carcinoma in
Mariano Bedoya +3 more
doaj +1 more source