Liquid biopsy epigenetics: establishing a molecular profile based on cell‐free DNA
Molecular Oncology, EarlyView.Cell‐free DNA (cfDNA) fragments in plasma from cancer patients carry epigenetic signatures reflecting their cells of origin. These epigenetic features include DNA methylation, nucleosome modifications, and variations in fragmentation. This review describes the biological properties of each feature and explores optimal strategies for harnessing cfDNA ...
Christoffer Trier Maansson +2 more
wiley +1 more source
An Educational Curriculum for Residents, Advanced Practice Providers, and Fellows in Cardiac Intensive Care Units. [PDF]
JACC AdvCarnicelli AP +14 more
europepmc +1 more source
Equal Employment Opportunity Commission, Plaintiff, -against SPS Temporaries, Inc,; Professional Personnel Management Corporation; Jamestown Container Lockport, Inc, doing business as Jamestown Container Companies; Jamestown Container Corp, doing business as Jamestown Container Companies; and Whiting Door Manufacturing Corp., Defendants. [PDF]
, 2005 Elfvin, Judge John T.
core +1 more source
Intein‐based modular chimeric antigen receptor platform for specific CD19/CD20 co‐targeting
Molecular Oncology, EarlyView.CARtein is a modular CAR platform that uses split inteins to splice antigen‐recognition modules onto a universal signaling backbone, enabling precise, scarless assembly without re‐engineering signaling domains. Deployed here against CD19 and CD20 in B‐cell malignancies, the design supports flexible multi‐antigen targeting to boost T‐cell activation and
Pablo Gonzalez‐Garcia +9 more
wiley +1 more source
Equal Employment Opportunity Commission, Plaintiff, Sretta Reese, Bonnie Centers, Fran Howard, & Melinda Cochran, Intervening Plaintiffs, v. Physician\u27s Services, P.S.C., Defendant. [PDF]
, 2007 Hood, Judge Joseph M.
core +1 more source
Molecular Oncology, EarlyView.Clinical trials on PARP inhibitors in urothelial carcinoma (UC) showed limited efficacy and a lack of predictive biomarkers. We propose SLFN5, SLFN11, and OAS1 as UC‐specific response predictors. We suggest Talazoparib as the better PARP inhibitor for UC than Olaparib.
Jutta Schmitz +15 more
wiley +1 more source
Teaching Clinical Reasoning in Health Care Professions Learners Using AI-Generated Script Concordance Tests: Mixed Methods Formative Evaluation. [PDF]
JMIR Form ResHudon A, Phan V, Charlin B, Wittmer R.
europepmc +1 more source
Equal Employment Opportunity Commission, Plaintiff, and Steve Garcia by and through his guardian, Mary Ann Kluck by and through her guardian, Cristina Gutierrez-Walter, David Laborin, Juan Rivera by and through his guardian, Plaintiff-Intervenors, vs. Aztec Inn Properties, LLC., an Arizona Corporation, dba Clarion Hotel - Randolph Park; HSL Properties Financial Corporation, an Arizona Corporation, Defendants. [PDF]
, 2004 Collins, Judge Raner C.
core +1 more source