Results 141 to 150 of about 971,013 (360)

A Cre‐dependent lentiviral vector for neuron subtype‐specific expression of large proteins

open access: yesFEBS Letters, EarlyView.
We designed a versatile and modular lentivector comprising a Cre‐dependent switch and self‐cleaving 2A peptide and tested it for co‐expression of GFP and a 2.8 kb gene of interest (GOI) in mouse cortical parvalbumin (PV+) interneurons and midbrain dopamine (TH+) neurons.
Weixuan Xue   +6 more
wiley   +1 more source

Misjudging [PDF]

open access: yes, 2007
article published in law journalJudging is difficult. This is obviously so in cases where the law is unclear or the facts are uncertain. But even in those cases where the law is as clear as it can be, and where the relevant facts have been fully ...
Guthrie, Chris
core   +3 more sources

Fair Trial Principles in the Basis of Judges Considering Decisions Based on Testimonium De Auditu [PDF]

open access: bronze, 2021
Yanels Garsione Damanik   +5 more
openalex   +1 more source

Targeting EZH2 reverses thyroid cell dedifferentiation and enhances iodide uptake in anaplastic thyroid cancer

open access: yesFEBS Letters, EarlyView.
Anaplastic thyroid cancer (ATC) lacks iodide uptake ability due to MAPK activation increasing the expression of the histone methyltransferase EZH2, which represses thyroid differentiation genes (TDGs) such as the sodium iodide symporter (NIS). Dual inhibition of MAPK (U0126) and EZH2 (EPZ6438/Tazemetostat) reverses this mechanism, thus restoring TDG ...
Diego Claro de Mello   +6 more
wiley   +1 more source

WAYS OF RAISING OF PRESTIGE OF JUSTICE OF THE PEACE

open access: yesRussian Journal of Economics and Law, 2007
The author raises the problem of increasing of prestige of Justice of the Peace. He considers problems that must be solved for raising the prestige, considers ways of achieving this aim.
T. A. Savina
doaj  

United Kingdom judges and European integration [PDF]

open access: yes, 2015
The British, specifically the English, are widely regarded as awkward partners in the European project. Much of the criticism has come from anti-European integration politicians.
Birkinshaw, Patrick
core  

Halu-J: Critique-Based Hallucination Judge [PDF]

open access: green
Binjie Wang   +3 more
openalex   +1 more source

By dawn or dusk—how circadian timing rewrites bacterial infection outcomes

open access: yesFEBS Letters, EarlyView.
The circadian clock shapes immune function, yet its influence on infection outcomes is only beginning to be understood. This review highlights how circadian timing alters host responses to the bacterial pathogens Salmonella enterica, Listeria monocytogenes, and Streptococcus pneumoniae revealing that the effectiveness of immune defense depends not only
Devons Mo   +2 more
wiley   +1 more source

L’insegnamento delle conferenze messicane: il giudice quale motore di trasformazione sociale [PDF]

open access: yesDemocrazia e Diritti Sociali
The paper concerns the contribution given by Calamandrei with the Mexican conferences to the transformative constitutionalism that spread in Latin America. In particular, it dwells on the role of the judge as an engine of social transformation.
Elena Bindi
doaj  

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