Results 211 to 220 of about 291,689 (288)

Targeting GRP78 and the Proteostasis Network to Break the Therapeutic Ceiling in Neuroendocrine Prostate Cancer

open access: yesiNew Medicine, EarlyView.
ABSTRACT HSPA5 (also known as GRP78/BiP) is a master regulator of the endoplasmic reticulum (ER) stress response and a key node in the proteostasis network. In neuroendocrine prostate cancer (NEPC), an aggressive, therapy‐refractory lineage that emerges under pressure from androgen receptor (AR) directed therapies, GRP78 is upregulated and co‐opted to ...
Amos Olalekan Akinyemi   +14 more
wiley   +1 more source

Empowering Adolescents for Sustainable and Inclusive Careers: A Quasi‐Experimental Evaluation of a Life Design‐Based Intervention

open access: yesJournal of Adolescence, EarlyView.
ABSTRACT Background Adolescents must plan their educational and occupational futures in a context shaped by globalization, social inequalities, and environmental crises. Although career guidance increasingly emphasizes sustainable and inclusive development, empirical interventions integrating social justice, sustainability, and critical consciousness ...
Sara Santilli   +5 more
wiley   +1 more source

Professional liability in dentistry: structure and causes of judicial litigation. [PDF]

open access: yesJ Forensic Odontostomatol
Di Lorenzo P   +6 more
europepmc   +1 more source

Group Agency and Egalitarian Corporate Structure: The Epistemic, Incentive, and Control Dimensions

open access: yesJournal of Applied Philosophy, EarlyView.
ABSTRACT What constitutes a good corporate agent? The article answers this question by critically applying List and Pettit's theory of group agency, which emphasizes three crucial dimensions of organizational design: epistemic quality, incentive compatibility, and control.
Chi Kwok, Chris Man‐Kong Li
wiley   +1 more source

Navigating the Map of Environmental-policy Narratives and its Influence within the Conservation Network of the Colombian-Peruvian Amazon. [PDF]

open access: yesEnviron Manage
González-Rodríguez CE   +4 more
europepmc   +1 more source

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