Results 101 to 110 of about 858,076 (334)

ST6GAL1‐Mediated Sialylation Stabilizes PD‐L1 and Drives Immunosuppressive Tumor Microenvironment in Colorectal Cancer

open access: yesAdvanced Science, EarlyView.
ST6GAL1 plays a critical role in tumor progression and immune regulation in colorectal cancer (CRC). Its depletion significantly suppresses the malignant phenotype of CRC cells and enhances the efficacy of anti‐PD‐L1 therapy. High ST6GAL1 expression promotes an immune‐activated tumor microenvironment (TME), characterized by increased infiltration of ...
Ximo Xu   +15 more
wiley   +1 more source

Constitutional rights and judicial review

open access: yesJurisprudence, 2017
Alon Harel’s Why Law Matters offers an avowedly non-instrumentalist account of rights, public institutions, entrenched constitutional rights, and judicial review.1 There is much of great interest i...
openaire   +3 more sources

The paradoxes of the theory of imprévision in the new French law of contract: a judicial deterrent? [PDF]

open access: yes, 2019
As part of the reform of the law of contracts,the theory of imprévision is now enshrined in Article 1195 CC of the French Civil Code. The novelty of this article lies essentially in the new judicial power of review. As this paper shows, Article 1195 CC
Pedamon, C., Pedamon, C.
core  

Cracking the Valence Code: Patterned Facial Kinematics and Neural Signatures of Emotional Expressions in Mice

open access: yesAdvanced Science, EarlyView.
An AI‐powered system decodes emotional valence from mouse facial expressions, identifying ear dynamics as key indicators. By integrating facial kinematics with synchronized neural recordings, this approach establishes a direct link between behavior and brain activity, advancing automated emotion recognition in animal models.
Yujia Chen   +9 more
wiley   +1 more source

Judicial review, reasons and technology: a glance at constitutionalism and democracy [PDF]

open access: yes, 2012
Judicial review reflects the level of commitment between constitutionalism and democracy in contemporary States. Yet democracy as the sovereign government of the people implies a tension with constitutionalism as the rule of law.
Karam de Chueiri, Vera
core  

Seek Justice, Not Just Deportation: How to Improve Prosecutorial Discretion in Immigration Law [PDF]

open access: yes, 2014
Bipartisan politics has prevented meaningful reform to a system in dire need of solutions: Immigration. Meanwhile there are eleven million noncitizens with no valid immigration status who currently reside in the United States and the Department of ...
Corcoran, Erin B.
core   +3 more sources

Onion‐Mitochondria Inhibit Lipopolysaccharide‐Induced Acute Lung Injury by Shaping Lung Macrophage Mitochondrial Function

open access: yesAdvanced Science, EarlyView.
Proposed model of orally administered onion mitochondria (O‐Mit) uptake by lung macrophages and fuse with macrophage mitochondria (M‐Mit). This fusion reprograms the metabolism of dysfunctional M‐Mit in lipopolysaccharide‐induced murine acute lung injury by modulating dynamin‐related protein 1 (DRP1) phosphorylation and cardiolipin peroxidation ...
Qingbo Xu   +13 more
wiley   +1 more source

Judicial Review as a Response to Political Posturing [PDF]

open access: yes, 2013
We use an agency model to analyze the impact of judicial review on the incentives of elected leaders to “posture” by enacting bold but ill-advised policies.
Fox, Justin, Stephenson, Matthew Caleb
core   +1 more source

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