Results 181 to 190 of about 1,084 (236)

Dimerization of human PARP15 is required for NAD+ binding and automodification

The FEBS Journal, EarlyView.
This study provides an integrated structural model of human PARP15. Biophysical, enzymatic, and cell‐based analyses identify the dimer as the active oligomeric state capable of binding the substrate NAD+. A co‐crystal structure with a non‐hydrolyzable substrate analog BAD reveals the molecular basis for the dimerization requirement.
Anna Tuovinen, Johan Pääkkönen, Mirko M. Maksimainen, Lea Hirschen, Heli I. Hentilä, Marie Tauscher, Bernhard Lüscher, Carlos Vela‐Rodríguez, Patricia Korn, Lari Lehtiö   +9 more
wiley   +1 more source

Forensic Mental Health Nurses' Perceptions and Experiences of Trauma-Informed Care in a High-Secure Hospital. [PDF]

J Forensic Nurs
Roberts C, Luder M, McMullen C, Cole R, Dignam P, Ward N, Ireland M.   +6 more
europepmc   +1 more source

Religiosity and Debt Maturity: International Evidence

Financial Review, EarlyView.
ABSTRACT This paper examines the association between country‐level religiosity and corporate debt maturity. We develop competing predictions reflecting creditor‐ and borrower‐side channels through which religiosity may favor either shorter or longer maturity. Using 407,399 firm‐year observations from 56 countries and territories over 1996–2021, we find
Xingyu Chen, Dequan Jiang, Xin Liu, Changqiu Yu, Steven Xiaofan Zheng   +4 more
wiley   +1 more source

Perceived Public Stigma Toward Psychological Help: Psychometric Validation of the Stigma Scale for Receiving Psychological Help Among Chinese Law Students. [PDF]

Behav Sci (Basel)
Wang T, Huang QL, Li W.
europepmc   +1 more source

The Politics of Pointing: Lessing's Fingerzeig and the Limits of Figural Reading

The German Quarterly, EarlyView.
Abstract Lessing's Fingerzeig—a “pointer” that guides without determining judgment—has often been treated as a stylistic habit rather than a hermeneutic principle. This essay reconstructs it as an ethics of interpretation, a gesture that orients without completing and leaves judgment to whoever follows.
Matthew Thomas Stoltz
wiley   +1 more source

Perception of clinical management in the child and adolescent population with acute mental health conditions. [PDF]

Rev Cuid
Mondaca Pavié LE, Rivas Riveros EE, Sepúlveda Rivas CC.   +2 more
europepmc   +1 more source

Polarization and rule of law crisis-insights from Poland. [PDF]

Z Vgl Polit
Solska M.
europepmc   +1 more source

Neuroethics and treatment without consent. [PDF]

CNS Spectr
Kennedy HG, Davoren M.
europepmc   +1 more source

Provision of dementia-specific care in nursing homes in North Rhine-Westphalia (Germany) - analysis of person-centered practices and related problems within a holistic multiple case study. [PDF]

BMC Nurs
Schmüdderich K, Fahsold A, Dörner J, Roes M, Palm R, Holle B.   +5 more
europepmc   +1 more source

Effects of stricter legislation on coercive measures in child and adolescent psychiatric care: a qualitative interview study with staff. [PDF]

BMC Psychiatry
Moell A, Rozental A, Buchmayer S, Kaltiala R, Långström N.   +4 more
europepmc   +1 more source