Results 81 to 90 of about 3,431 (206)

Natural Products in Cancer Prevention and Therapy: Current Challenges and Future Directions

open access: yesMedComm, Volume 7, Issue 2, February 2026.
Natural products play a pivotal role in cancer therapy. They induce cancer cell death by reprogramming four metabolic pathways while precisely targeting the tumor microenvironment and immune cells. These compounds not only leverage novel delivery systems for innovative applications but also demonstrate unique therapeutic efficacy across clinical stages:
Ruimiao Qian   +8 more
wiley   +1 more source

INVESTIGATION OF THE EFFECTS OF JUGLONE AND CISPLATIN ON BREAST CANCER CELL LINES

open access: yesInternational Journal of Health Services Research and Policy
Breast cancer is one of the most commonly diagnosed malignancies worldwide, accounting for approximately 11% of all cancer-related deaths. Cisplatin induces DNA damage, thereby leading to apoptotic cell death, while juglone, a phytochemical compound ...
Selda Şimşek   +2 more
doaj   +1 more source

Photo‐Autocatalysis: Insights From Light‐Driven Self‐Catalyzed Organic Transformations

open access: yesChemistry – An Asian Journal, Volume 21, Issue 2, 28 January 2026.
This perspective highlights recent advancements in photo‐autocatalytic reactions—light‐driven processes characterized by self‐accelerating kinetics. We explore the underlying mechanisms, demonstrating how photo‐autocatalysis can be realized either through a single photo‐autocatalyst or through a combination of a photocatalyst and an autocatalyst, and ...
James Shao‐Jiun Yang   +2 more
wiley   +1 more source

In vitro nematicidal activity of naphthoquinones against the root-lesion nematode Pratylenchus thornei

open access: yesPhytopathologia Mediterranea, 2017
The root-lesion nematode Pratylenchus thornei is a widely distributed and important parasite of cereals and legumes. As migratory endoparasites, P. thornei are difficult to manage  because they enter and leave host roots and may remain quiescent inside ...
Ivânia ESTEVES   +5 more
doaj   +1 more source

Exploring the Neuroprotective Promise of Functional Fruit Phytochemicals

open access: yesJournal of Food Biochemistry, Volume 2026, Issue 1, 2026.
Neurodegenerative diseases, including Alzheimer’s disease, represent a significant global clinical challenge, since existing treatments primarily manage symptoms rather than addressing the complex and multifactorial underlying pathologies. Functional fruits, including both their edible and nonedible parts, are rich in bioactive phytochemicals such as ...
Tebalelo Lehlaleroa   +5 more
wiley   +1 more source

Regiochemical control in the addition of aryl N-sulphinylamines to juglone and juglone derivatives

open access: yes, 1998
Regiochemistry of addition of N-aryl-sulphinylamines to juglone and juglone derivatives is controlled by the nature of the oxygen function at 5 ...
Amarasekara, Ananda S.   +1 more
core  

Impact of Juglone, a PIN1 İnhibitor, on Oral Carcinogenesis Induced by 4-Nitroquinoline-1-Oxide (4NQO) in Rat Model

open access: yesMedicina
Background and Objectives: PIN1 is overexpressed in several human cancers, including prostate cancer, breast cancer, and oral squamous carcinomas. Juglone (J), derived from walnut, was reported to selectively inhibit PIN1 by modifying its sulfhydryl ...
Olgun Topal   +7 more
doaj   +1 more source

Alleviation of allelochemical juglone-induced phytotoxicity in tobacco plants by proline

open access: yes, 2015
Juglone (5-hydroxy-1,4-naphthoquinone) is an important allelochemical in walnut trees (Juglans nigra L.). Its allelopathic potential has been reported in different plant species.
Tzen-Yuh Chiang (138945)   +9 more
core   +1 more source

Enhanced antimicrobial potency and stability of juglone/β-cyclodextrin inclusion complexes: a comparative study of formulation methods

open access: yesMaterials Research Express
Juglone (5-hydroxy-1,4-naphthoquinone), a natural antifungal and antibacterial agent derived from walnut trees, possesses significant therapeutic potential limited by its low water solubility and instability in varying pH and temperature conditions This ...
Pelin Pelit Arayıcı   +3 more
doaj   +1 more source

Juglone induces apoptosis of tumor stem-like cells through ROS-p38 pathway in glioblastoma

open access: yesBMC Neurology, 2017
Background Juglone is a natural pigment, which has cytotoxic effect against various human tumor cells. However, its cytotoxicity to glioma cells, especially to tumor stem-like cells (TSCs) has not been demonstrated.
Jinfeng Wu   +8 more
doaj   +1 more source

Home - About - Disclaimer - Privacy