Results 221 to 230 of about 661,358 (366)

ESG‐1‐60 and ESG‐1‐61: Novel dopamine D3 receptor‐preferring partial agonists/antagonists that inhibit cocaine taking and seeking in rodents

open access: yesBritish Journal of Pharmacology, EarlyView.
Abstract Background and Purpose Preclinical studies suggest that highly selective dopamine D3 receptor (D3R) antagonists or partial agonists hold promise for treating substance use disorders. However, their limited effectiveness in reducing cocaine self‐administration is a major drawback.
Omar Soler‐Cedeño   +9 more
wiley   +1 more source

Pharmacokinetics of escalating single‐dose administration of cannabidiol to cats

open access: yesJournal of Veterinary Pharmacology and Therapeutics, Volume 46, Issue 1, Page 25-33, January 2023., 2023
Abstract This study aimed to assess the single‐dose pharmacokinetics and tolerability of a cannabidiol (CBD) isolate in sunflower oil with escalating oral doses in eight healthy, purpose‐bred cats. Eight cats were randomized into six dosing groups of four cats each.
Aaron J. Rozental   +5 more
wiley   +1 more source

Behavioural and pharmacokinetic analysis of heroin and cocaine self‐administration: Effects of timeout on self‐administration and choice in male rats

open access: yesBritish Journal of Pharmacology, EarlyView.
Background and Purpose Heroin and cocaine users tailor their dosage, frequency and administration route to maximise the drugs' effects or prevent withdrawal symptoms. Counterintuitively, preclinical self‐administration and choice experiments employ, almost invariably and regardless of the pharmacokinetic properties of the drug under examination, fixed ...
Ginevra D'Ottavio   +18 more
wiley   +1 more source

Single‐dose pharmacokinetics of telmisartan oral solution and effect of feeding in dogs

open access: yesJournal of Veterinary Pharmacology and Therapeutics, Volume 46, Issue 1, Page 17-24, January 2023., 2023
Abstract Telmisartan is an angiotensin II receptor blocker that has great potential to improve the treatment of hypertension, proteinuria, and cardiovascular disease in dogs. A feline‐approved telmisartan oral solution (TOS) is available, but this formulation has not been evaluated in dogs.
Allison G. Bechtel   +2 more
wiley   +1 more source

Leadless pacemaker implantation via the internal jugular vein. [PDF]

open access: yesEuropace
Molitor N   +5 more
europepmc   +1 more source

Jugular Vein Cannulation for Hemodialysis Access

open access: bronze, 1988
Josep M. Campistol   +3 more
openalex   +1 more source

An Ectopic External Jugular Vein Draining into the Axillary Vein: a Rare Anatomical Variation with Clinical Implications. [PDF]

open access: yesActa Med Acad
Daskalopoulou D   +6 more
europepmc   +1 more source

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