Results 241 to 250 of about 53,161 (355)

Fetal growth restriction adversely impacts trajectory of hippocampal neurodevelopment and function

open access: yesBrain Pathology, EarlyView.
Hippocampal neuron dendritogenesis occurs rapidly in late fetal gestation and forms the foundation for connectivity and long term function. Fetal growth restriction caused by placental insufficiency is associated with reduced dendritogenesis in hippocampal neurons, resulting in a significant decrease in the trajectory of neuro‐development.
Ingrid Dudink   +15 more
wiley   +1 more source

Palatability, glycemic, and insulinemic responses to various carbohydrate formulations: Alternatives for the diagnosis of insulin dysregulation in horses?

open access: yesJournal of Veterinary Internal Medicine, Volume 37, Issue 1, Page 282-291, January/February 2023., 2023
Abstract Background Oral glycemic challenge (GC) tests are recommended for diagnosis of insulin dysregulation (ID). Various protocols are used, but all have limitations in terms of palatability, ease of use, variable composition, geographic availability, or some combination of these.
Tobias Warnken   +6 more
wiley   +1 more source

ESG‐1‐60 and ESG‐1‐61: Novel dopamine D3 receptor‐preferring partial agonists/antagonists that inhibit cocaine taking and seeking in rodents

open access: yesBritish Journal of Pharmacology, EarlyView.
Abstract Background and Purpose Preclinical studies suggest that highly selective dopamine D3 receptor (D3R) antagonists or partial agonists hold promise for treating substance use disorders. However, their limited effectiveness in reducing cocaine self‐administration is a major drawback.
Omar Soler‐Cedeño   +9 more
wiley   +1 more source

Pharmacokinetics of escalating single‐dose administration of cannabidiol to cats

open access: yesJournal of Veterinary Pharmacology and Therapeutics, Volume 46, Issue 1, Page 25-33, January 2023., 2023
Abstract This study aimed to assess the single‐dose pharmacokinetics and tolerability of a cannabidiol (CBD) isolate in sunflower oil with escalating oral doses in eight healthy, purpose‐bred cats. Eight cats were randomized into six dosing groups of four cats each.
Aaron J. Rozental   +5 more
wiley   +1 more source

Cardiology for dummies [PDF]

open access: yes, 2011
van Loon, Gunther
core  

A Technique for Portacaval Transposition. [PDF]

open access: yes, 1961
Child   +7 more
core   +1 more source

Behavioural and pharmacokinetic analysis of heroin and cocaine self‐administration: Effects of timeout on self‐administration and choice in male rats

open access: yesBritish Journal of Pharmacology, EarlyView.
Background and Purpose Heroin and cocaine users tailor their dosage, frequency and administration route to maximise the drugs' effects or prevent withdrawal symptoms. Counterintuitively, preclinical self‐administration and choice experiments employ, almost invariably and regardless of the pharmacokinetic properties of the drug under examination, fixed ...
Ginevra D'Ottavio   +18 more
wiley   +1 more source

Single‐dose pharmacokinetics of telmisartan oral solution and effect of feeding in dogs

open access: yesJournal of Veterinary Pharmacology and Therapeutics, Volume 46, Issue 1, Page 17-24, January 2023., 2023
Abstract Telmisartan is an angiotensin II receptor blocker that has great potential to improve the treatment of hypertension, proteinuria, and cardiovascular disease in dogs. A feline‐approved telmisartan oral solution (TOS) is available, but this formulation has not been evaluated in dogs.
Allison G. Bechtel   +2 more
wiley   +1 more source

Jugular Vein Cannulation for Hemodialysis Access

open access: bronze, 1988
Josep M. Campistol   +3 more
openalex   +1 more source

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