Results 61 to 70 of about 64,522 (306)
AIMS MathematicsIn this manuscript, we investigate the dynamics of higher-order polynomials with complex coefficients by employing the Jungck–Noor iteration scheme (one of the iterative methods) in conjunction with $ s $-convexity, which controls the weighting of ...
Anita Tomar +3 more
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LDAcoop: Integrating non‐linear population dynamics into the analysis of clonogenic growth in vitro
Molecular Oncology, EarlyView.Limiting dilution assays (LDAs) quantify clonogenic growth by seeding serial dilutions of cells and scoring wells for colony formation. The fraction of negative wells is plotted against cells seeded and analyzed using the non‐linear modeling of LDAcoop.
Nikko Brix +13 more
wiley +1 more source
Peroxidasin enables melanoma immune escape by inhibiting natural killer cell cytotoxicity
Molecular Oncology, EarlyView.Peroxidasin (PXDN) is secreted by melanoma cells and binds the NK cell receptor NKG2D, thereby suppressing NK cell activation and cytotoxicity. PXDN depletion restores NKG2D signaling and enables effective NK cell–mediated melanoma killing. These findings identify PXDN as a previously unrecognized immune evasion factor and a potential target to improve
Hsu‐Min Sung +17 more
wiley +1 more source
Equilibrium measures on Julia sets of random quadratic polynomials [PDF]
, 2023 Krzysztof Lech, Anna Zdunik
openalex +1 more source
Mandelbrot and Julia Sets of Transcendental Functions Using Picard–Thakur Iteration
Fractal and Fractional, 2023 The majority of fractals’ dynamical behavior is determined by escape criteria, which utilize various iterative procedures. In the context of the Julia and Mandelbrot sets, the concept of “escape” is a fundamental principle used to determine whether a ...
Ashish Bhoria +2 more
doaj +1 more source
SIRT4 positively regulates autophagy via ULK1, but independently of HDAC6 and OPA1
FEBS Open Bio, EarlyView.Cells expressing SIRT4 (H161Y), a catalytically inactive mutant of the sirtuin SIRT4, fail to upregulate LC3B‐II and exhibit a reduced autophagic flux under stress conditions. Interestingly, SIRT4(H161Y) promotes phosphorylation of ULK1 at S638 and S758 that are associated with inhibition of autophagy initiation.
Isabell Lehmkuhl +13 more
wiley +1 more source
FEBS Open Bio, EarlyView.Chemoresistance in bladder cancer: Macrophage recruitment associated with CXCL1, CXCL5 and CXCL8 expression is characteristic of Gemcitabine/Cisplatin (Gem/Cis) Non‐Responder tumors (right side) while Responder tumors did not show substantial tumor‐stromal crosstalk (left side). All biological icons are attributed to Bioicons: carcinoma, cancerous‐cell‐
Sophie Leypold +11 more
wiley +1 more source
Promiscuous stimulation of HSP70 ATPase activity by parasite‐derived J‐domains
FEBS Open Bio, EarlyView.The malaria parasite Plasmodium falciparum exports three highly homologous yet functionally divergent J‐domain proteins into human erythrocytes. Here, we show that J‐domains isolated from all three proteins effectively stimulate the ATPase activity of both endogenous host and exported parasite HSP70 chaperones.
Julian Barth +6 more
wiley +1 more source
Fractals via Generalized Jungck–S Iterative Scheme
Discrete Dynamics in Nature and Society, 2021 The purpose of this research is to introduce a Jungck–S iterative method with m,h1,h2–convexity and hence unify different comparable iterative schemes existing in the literature.
Zhihua Chen +3 more
doaj +1 more source