Rapid screening of staphylokinase protein variants using an unpurified cell‐free expression system
An unpurified cell‐free protein synthesis (CFPS) platform enables rapid functional screening of staphylokinase variants. Direct plasminogen‐activation assays performed in microplate format provide real‐time activity readouts, allowing rapid identification and ranking of variants with improved or reduced fibrinolytic activity without protein ...
Maria Tomková +3 more
wiley +1 more source
Smartphone-Based Assessment of the Stretch-Shortening Cycle: Validity and Reliability of the My Jump Lab App for Measuring the Dynamic Rebound Index. [PDF]
Balsalobre-Fernández C.
europepmc +1 more source
Evolutionarily divergent DUF4465 domains have a common vitamin B12‐binding function
We show that DUF4465 family proteins, widespread across bacteria from gut microbiomes, hydrothermal vents, and soil, share a common vitamin B12‐binding function. These augmented β‐jellyroll proteins bind vitamin B12 via extended loops. Our findings establish sequence‐diverse DUF4465 proteins as a widespread class of B12‐binding proteins, highlighting ...
Charlea Clarke +4 more
wiley +1 more source
Jump assessment on a force plate-an approach to quantify subtle lower limb neuromuscular deficits in people with multiple sclerosis. [PDF]
Geßner A +4 more
europepmc +1 more source
Bioscience students were asked for their opinions on the value and teaching of skills. 204 responded that teamwork, time management and study skills are necessary to reach University, that scientific writing, research, laboratory and presentation skills are taught effectively during their studies, while other skills are gained inherently through study ...
Janella Borrell, Susan Crennell
wiley +1 more source
Associations Between Isokinetic Knee Strength at Different Angular Velocities and Explosive Jump Performance in Young Female Athletes: A Pilot Study. [PDF]
Falat Leütterová D, Sučka J.
europepmc +1 more source
Why human connection is the true metric of research success
Human‐centred mentorship can be shaped by mentor attributes, actions, intrinsic drive and career ambition. Drawing on reflections across Singapore and France, as well as workshop insights from FEBS‐IUBMB ENABLE 2024, this article shows that human‐centred mentorship creates the conditions for sustainable growth, well‐being and retention in research ...
Timothy Lin Yun Tan +3 more
wiley +1 more source
Effects of Various Exercise Interventions on Sprint Performance and Jump Height in Soccer Players: A Systematic Review and Network Meta-Analysis. [PDF]
Wang Y, Zhang M, Luo Z.
europepmc +1 more source
Chemotherapy side effects significantly impact cancer survivors' quality of life. Using protein levels in blood samples from breast cancer patients before and after 12 weeks of taxane treatment, we detected treatment‐dependent changes in calcium signaling and aging pathways associated with cancer recurrence.
Saira Munshani +6 more
wiley +1 more source
Thermal and immunological stress modulate the locomotor performance of female <i>Xenopus laevis</i> frogs. [PDF]
Oliveira TG +4 more
europepmc +1 more source

