Results 41 to 50 of about 121,419 (269)

Effects of Velocity Loss Threshold during Resistance Training on Strength and Athletic Adaptations: A Systematic Review with Meta-Analysis

open access: yesApplied Sciences, 2022
This study aimed to systematically review the effects of the different velocity loss (VL) thresholds during resistance training (RT) on strength and athletic adaptations. The VL was analyzed as both a categorical and continuous variable.
Alejandro Hernández-Belmonte   +1 more
doaj   +1 more source

The planar cell polarity protein Vangl2 interacts with the PDZ‐domains of Scribble but not with a unique PDZ‐like domain in Inturned

open access: yesFEBS Letters, EarlyView.
Structural and biochemical characterisations show that the planar cell polarity (PCP) protein Inturned harbours a unique PDZ‐like domain that does not bind canonical PDZ‐binding motifs (PBMs) like that of another PCP protein Vangl2. In contrast, the apical‐basal polarity protein Scribble contains four PDZ domains that bind Vangl2, but one PDZ domain ...
Stephan Wilmes   +4 more
wiley   +1 more source

Tau acetylation at K331 has limited impact on tau pathology in vivo

open access: yesFEBS Letters, EarlyView.
We mapped tau post‐translational modifications in humanized MAPT knock‐in mice and in amyloid‐bearing double knock‐in mice. Acetylation within the repeat domain, particularly around K331, showed modest increases under amyloid pathology. To test functional relevance, we generated MAPTK331Q knock‐in mice.
Shoko Hashimoto   +3 more
wiley   +1 more source

The influence of maturation on functional performance and injury markers in male youth

open access: yesCogent Medicine, 2019
The aim of this study was to identify the influence of maturation on sprinting and jump performances, whilst quantifying injury markers in 95 youth males (age 13.2–15.7y).
Regan J. Standing   +3 more
doaj   +1 more source

Calpain small subunit homodimerization is robust and calcium‐independent

open access: yesFEBS Letters, EarlyView.
Calpains dimerize via penta‐EF‐hand (PEF) domains. Using single‐molecule force spectroscopy, we measured the strength and kinetics of PEF–PEF homodimer binding. The interaction is robust, shows a transient conformational step before dissociation, and remains largely insensitive to Ca2+.
Nesha May O. Andoy   +4 more
wiley   +1 more source

Concurrent Validity and Reliability of a Free Smartphone Application for Evaluation of Jump Height

open access: yesJournal of Functional Morphology and Kinesiology
Background/Objectives: Jump test assessment is commonly used for physical tests, with different type of devices used for its evaluation. The purpose of the present study was to examine the validity and reliability of a freely accessible mobile ...
Amândio Dias   +8 more
doaj   +1 more source

Magnitude, Frequency, and Accumulation: Workload Among Injured and Uninjured Youth Basketball Players

open access: yesFrontiers in Sports and Active Living, 2021
Overuse injuries are common in basketball. Wearable technology enables the workload to be monitored in sport settings. However, workload–injury models lack a biological basis both in the metrics recorded and how workload is accumulated.
Lauren C. Benson   +14 more
doaj   +1 more source

Structural insights into an engineered feruloyl esterase with improved MHET degrading properties

open access: yesFEBS Letters, EarlyView.
A feruloyl esterase was engineered to mimic key features of MHETase, enhancing the degradation of PET oligomers. Structural and computational analysis reveal how a point mutation stabilizes the active site and reshapes the binding cleft, expading substrate scope.
Panagiota Karampa   +5 more
wiley   +1 more source

Reliability of the Hop Test and Asymmetry Index in University Athletes: A Cross-Sectional Study Assessing Injury Risk

open access: yesResearch in Sport Education and Sciences
This study aims to assess the reliability of hop tests among healthy university athletes and to identify leg asymmetries through these assessments. A cohort of 212 university athletes, active in sports, participated in the study.
Alper Karadağ   +2 more
doaj   +1 more source

Diversity and complexity in neural organoids

open access: yesFEBS Letters, EarlyView.
Neural organoid research aims to expand genetic diversity on one side and increase tissue complexity on the other. Chimeroids integrate multiple donor genomes within single organoids. Self‐organising multi‐identity organoids, exogenous cell seeding, or enforced assembly of region‐specific organoids contribute to tissue complexity.
Ilaria Chiaradia, Madeline A. Lancaster
wiley   +1 more source

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