Results 81 to 90 of about 121,419 (269)

Mixed‐class J‐domain protein scaffolds promote expanded aggregate handling and multivalent Hsp70 engagement during functional disaggregase assembly

FEBS Letters, EarlyView.
Protein aggregates threaten proteostasis and cell health. In human cells, Hsp70–J‐domain protein‐based disaggregases remove aggregates, but how they assemble remains unclear. Our biochemical findings show that DNAJA2‐ and DNAJB1‐containing disaggregase scaffolds enhance luciferase aggregate targeting, and that Hsp70 recruitment by both J‐domain ...
Anna Szlachcic, Nadinath B. Nillegoda
wiley   +1 more source

Motion Planning for Bipedal Robot to Perform Jump Maneuver

Applied Sciences, 2018
The remarkable ability of humans to perform jump maneuvers greatly contributes to the improvements of the obstacle negotiation ability of humans. The paper proposes a jumping control scheme for a bipedal robot to perform a high jump. The half-body of the
Xinyang Jiang, Xuechao Chen, Zhangguo Yu, Weimin Zhang, Libo Meng, Qiang Huang   +5 more
doaj   +1 more source

Identification of a Shiga toxin A‐derived peptide internalized into Gb3 receptor‐bearing cells via interaction with the Shiga toxin B subunit

FEBS Letters, EarlyView.
The process of internalization of the Shiga toxin A subunit via formation of a complex with the Shiga toxin B subunit, which specifically binds to the Gb3 receptor. The peptide is designed to act as a carrier of drugs into cancer cells. Here, we explored the potential of peptides derived from the catalytic A subunit of Shiga toxin (STxA) to be drug ...
Giulia Opassi, João C. Encarnação, Valeria Napolitano, Grzegorz Dubin, Grzegorz Popowicz, Karl Andersson, U. Helena Danielson   +6 more
wiley   +1 more source

Forward Starting Option Pricing under Double Fractional Stochastic Volatilities and Jumps

Fractal and Fractional
This paper aims to provide an effective method for pricing forward starting options under the double fractional stochastic volatilities mixed-exponential jump-diffusion model.
Sumei Zhang, Haiyang Xiao, Hongquan Yong
doaj   +1 more source

Relación entre la fuerza máxima en squat y acciones de salto, sprint y golpeo de balón. (Relationship among maximal strength in squat exercise, jump, sprint and kicking ball performance.) [PDF]

Revista Internacional de Ciencias del Deporte, 2008
ResumenEl objetivo del presente estudio fue analizar las posibles relaciones entre la fuerza máxima en squat y accionesexplosivas de salto, sprint y golpeo de balón.
Alfredo Arija Blázquez, Daniel Juárez Santos-García, José María González Ravé, Rosa María Aceña Rubio, Fernando Navarro Valdivielso   +4 more
doaj  

Investigating transcription factor dynamics in health and disease using FRAP

FEBS Letters, EarlyView.
FRAP analysis of GFP‐tagged transcription factors reveals how molecular mobility and target engagement change in response to drug treatment. By combining live‐cell imaging, quantitative model fitting, and statistical analysis, this approach uncovers transcription factor dynamics linked to disease mechanisms, providing a powerful framework for ...
Kannan Govindaraj, Carolina Vazquez Garzon, Jose Joaquin Velasco, Janine N. Post   +3 more
wiley   +1 more source

Factors contributing to jump heights in two-foot running jumps with and without a basketball

Frontiers in Sports and Active Living
IntroductionTwo-foot running jumps (TFRJs) are used by basketball players during games and evaluations for maximum jump height with or without a ball.
Jun Ming Liu, Antonia Zaferiou
doaj   +1 more source

Short-Term Effects of Suspension Training on Strength and Power Performances

Journal of Functional Morphology and Kinesiology, 2018
Suspension Training (ST) workouts include a variety of movements requiring the individual to maintain balance while performing various resistance exercises in an interval fashion.
Giuseppe Francesco Giancotti, Andrea Fusco, Alice Iannaccone, Cristina Cortis   +3 more
doaj   +1 more source

Conserved binding mode but diverse interfaces of MreC‐PBP2 interactions

FEBS Letters, EarlyView.
The crystal structure of abMreC reveals a conserved two β‐barrel architecture and provides structural insights into its role within the bacterial elongasome. The abMreC–abPBP2 complex model identifies the molecular basis of MreC‐mediated PBP2 recognition, contributing to the regulation of peptidoglycan synthesis.
Hyunseok Jang, Hyo Been Jin, Chang Min Kim, So Yeon Lee, Hyun Ho Park   +4 more
wiley   +1 more source

Functional Movement Screen Scores and Physical Performance among Youth Elite Soccer Players

Sports, 2017
This study had two main objectives: (1) to determine if differences in Functional Movement Screen (FMS) scores exist between two levels of competition; and (2) to analyze the association between FMS individual and overall scores and physical performance ...
Bruno Silva, Filipe Manuel Clemente, Miguel Camões, Pedro Bezerra   +3 more
doaj   +1 more source