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A Depolarizing Leak in Sodium Bicarbonate Cotransporter NBCe1 Causes Brain Edema

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objectives SLC4A4 encodes electrogenic sodium bicarbonate cotransporter NBCe1, prominently expressed in kidney and brain. Recessive loss‐of‐function variants in SLC4A4 cause proximal renal tubular acidosis, no brain edema. In the brain, NBCe1 is expressed by astrocytes, where it regulates pH and mediates astrocyte volume changes.
Quinty Bisseling, Mark D. Parker, Sven Kerst, Richard A. Pasternack, Jacob Tondreau, Marjolein Breur, Gemma M. van Rooijen‐van Leeuwen, Davide Tonduti, Ettore Salsano, Alejandra Darling, Joanna A. E. van Wijk, Susanna Törnroth‐Horsefield, Marianna Bugiani, Petra J. W. Pouwels, Quinten Waisfisz, Marjo S. van der Knaap, Rogier Min   +16 more
wiley   +1 more source

Cruising and jumping: the effect of microplastics on the swimming behavior of copepods measured by 3D Lagrangian particle tracking velocimetry. [PDF]

Eur Phys J E Soft Matter
Michalec FG, Praud O, Lorite-Diez M, Cazin S, Souissi S, Climent E.   +5 more
europepmc   +1 more source

Relationship between lower limb neuromuscular and functional performance tests and sprint and agility in female volleyball players: a cross-sectional study. [PDF]

Front Physiol
Akgün S, Atıcı M, Bayrakdar A, Salkılıç EK, Anıl B, Akdemir E, Kumru D, Şebin K, Aksoy Y, Yılmaz AK.   +9 more
europepmc   +1 more source

Temporal Trends in Health-Related Components of Physical Fitness of European Children and Adolescents from 1965 to 2025: A Systematic Review of Data on 417,362 Participants from 20 Countries. [PDF]

Sports Med Open
Domingo-Del-Val D, Lozano-Berges G, Moradell A, Gómez-Bruton A, Matute-Llorente Á, Casajús JA.   +5 more
europepmc   +1 more source

Relationship Between Lower-Body Power and Sport-Specific Start Performance in International-Level BMX Riders. [PDF]

J Funct Morphol Kinesiol
Marcen-Cinca N, Bascuas PJ, Rabal-Pelay J.   +2 more
europepmc   +1 more source

Clearance Criteria for Determining Eligibility for Force Plate Testing After Anterior Cruciate Ligament Reconstruction: A Scoping Review. [PDF]

Medicina (Kaunas)
Christoffel L, Beaupre L, Nathanail S, Labban W, Sommerfeldt M, Westover L, Thornton GM.   +6 more
europepmc   +1 more source

Squat Jump and Bilateral and Unilateral Countermovement Jump Performance in Soccer Players 6 and 9 Months After Anterior Cruciate Ligament Reconstruction. [PDF]

Medicina (Kaunas)
Andrić N, Mikić M, Jakšić D, Molnar S, Javorac D, Milankov V.   +5 more
europepmc   +1 more source

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A Note on Diffusion Processes with Jumps

2018
We focus on stochastic diffusion processes with jumps occurring at random times. After each jump the process is reset to a fixed state from which it restarts with a different dynamics. We analyze the transition probability density function, its moments and the first passage time density.
giorno, virginia, Spina, Serena
openaire   +2 more sources

On Markov-Additive Jump Processes

Queueing Systems, 2002
The focus is on Markov-additive processes, which belong to the class of Markov jump processes. Markov-additive jump processes are defined as 2-dimensional Markov jump processes, which satisfy the condition that the transition probabilities depend on one dimension only.
openaire   +2 more sources