Results 201 to 210 of about 116,517 (298)

Activation of Kir4.1 Channels by 2‐D08 Promotes Myelin Repair in Multiple Sclerosis

open access: yesAdvanced Science, EarlyView.
Multiple sclerosis causes myelin loss and neurological dysfunction. This study shows that 2‐D08, a small molecule targeting Kir4.1 channels, promotes OPCs differentiation via FYN tyrosine kinase phosphorylation and the FYN/MYRF pathway. It significantly improves myelin repair and motor deficits in EAE mice and marmosets, highlighting its potential as a
Mingdong Liu   +17 more
wiley   +1 more source

Bacteria Optimize Tumble Bias to Strategically Navigate Surface Constraints

open access: yesAdvanced Science, EarlyView.
The study investigates how Escherichia coli optimizes tumble bias (TB) to navigate surface constraints effectively. Using single‐cell tracking and modeling, it reveals that bacterial surface residence time decreases with increasing TB, stabilizing near the wild‐type mean TB (≈0.25), where surface diffusivity peaks.
Antai Tao   +3 more
wiley   +1 more source

Zoborg: On‐Demand Climbing Control for Cyborg Beetles

open access: yesAdvanced Science, EarlyView.
A novel on‐demand climbing protocol enables Zoborg (a cyborg beetle from the living Zophobas morio) to seamlessly transition from horizontal floors to vertical walls. Multiple unrestrained mechanosensors allow wall sensing while electrical stimulation of the elytron initiates climbing. Leveraging the agile locomotion and exceptional adaptability of the
Lachlan Fitzgerald   +5 more
wiley   +1 more source

Comparison of the Prevalence and Location of Trigger Points in Dressage and Show-Jumping Horses. [PDF]

open access: yesAnimals (Basel)
Portier K   +5 more
europepmc   +1 more source

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