Subcellular heterogeneity of ryanodine receptor properties in ventricular myocytes with low T-tubule density [PDF]
, 2011 Rationale: In ventricular myocytes of large mammals, not all ryanodine receptor (RyR) clusters are associated with T-tubules (TTs); this fraction increases with cellular remodeling after myocardial infarction (MI).
AM Gomez +55 more
core +4 more sources
Multigene Next-Generation Sequencing Panel Identifies Pathogenic Variants in Patients with Unknown Subtype of Epidermolysis Bullosa: Subclassification with Prognostic Implications [PDF]
, 2017 Purpose: Epidermolysis bullosa (EB), the prototype of heritable blistering diseases, is caused by mutations in as many as 19 distinct genes. In this study, we evaluated the molecular basis of EB in 93 families, many of them of unknown subtype. Methods:
Abiri, Maryam +15 more
core +1 more source
Uterine natural killer cell heterogeneity: Lessons from mouse models [PDF]
, 2020 Natural killer (NK) cells are the most abundant lymphocytes at the maternal-fetal interface. Epidemiological data implicate NK cells in human pregnancy outcomes.
Sojka, Dorothy K
core +1 more source
Acta Obstetricia et Gynecologica Scandinavica, 2018 Our aim was to correlate junctional zone thickening and irregularity (junctional zone disease) and other ultrasonographic features of adenomyosis with the histopathology of the endometrial‐myometrial junctional zone.
C. Rasmussen, E. Hansen, M. Dueholm
semanticscholar +1 more source
Exclusion processes: short range correlations induced by adhesion and contact interactions [PDF]
, 2013 We analyze the out-of-equilibrium behavior of exclusion processes where agents interact with their nearest neighbors, and we study the short-range correlations which develop because of the exclusion and other contact interactions.
Ascolani, Gianluca +2 more
core +5 more sources
Modeling superimposed preeclampsia using Ang II (Angiotensin II) infusion in pregnant stroke-prone spontaneously hypertensive rats [PDF]
, 2018 Hypertensive disorders of pregnancy are the second leading cause of maternal deaths worldwide. Superimposed preeclampsia is an increasingly common problem and often associated with impaired placental perfusion. Understanding the underlying mechanisms and
Beattie, Elisabeth +7 more
core +2 more sources
P14.10: Predicting disruption of the junctional zone in Caesarean section deliveries
Ultrasound in Obstetrics and Gynecology, 2018 Pictures Figure 1 illustrates an example of a normal uterus with uniform Junctional Zone. Figure 2 demonstrates a uterus with presence of Caesarean scar and disrupted Junctional Zone. Conclusion Caesarean Scar has impact on the Junctional Zone.
N. Singhal +3 more
semanticscholar +1 more source
Penetrating trauma to the junctional zone needs aggressive management [PDF]
BMJ, 2007 Diagnostic laparoscopy or thoracoscopy can improve diagnosis of occult injuries to the diaphragm and reduce the risk of serious late ...
J, Ahmad +4 more
openaire +2 more sources
Adjuvant therapeutic potential of tonabersat in the standard treatment of glioblastoma : a preclinical F98 glioblastoma rat model study [PDF]
, 2019 Purpose Even with an optimal treatment protocol, the median survival of glioblastoma (GB) patients is only 12-15 months. Hence, there is need for novel effective therapies that improve survival outcomes.
Bonte, Ellen +11 more
core +1 more source
Uterine junctional zone and adenomyosis
Ultrasound in Obstetrics and Gynecology, 2022 The uterine junctional zone is the subendometrial area in the myometrium that contributes to peristalsis and aids in spermatozoa and blastocyst transport. Alterations in the appearance of the junctional zone on transvaginal sonography (TVS) or magnetic resonance imaging (MRI) are associated with adenomyosis.
Harmsen, M J +7 more
openaire +1 more source