Increased expression of STAT3 and SOCS3 in placenta from hyperglycemic rats
European Journal of Histochemistry, 2019 Signal transducer and activator of transcription 3 (STAT3) is a transcription factor that is activated by interleukin (IL)-6 and IL-10 that generate nearly opposing responses.
Vanessa Dela Justina +8 more
doaj +1 more source
Recessive mutation in tetraspanin CD151 causes Kindler syndrome-like epidermolysis bullosa with multi-systemic manifestations including nephropathy [PDF]
, 2018 Epidermolysis bullosa (EB) is caused by mutations in as many as 19 distinct genes. We have developed a next-generation sequencing (NGS) panel targeting genes known to be mutated in skin fragility disorders, including tetraspanin CD151 expressed in ...
Abiri, Maryam +15 more
core +1 more source
Asian Pacific Journal of Reproduction, 2015 Objective: To examine the potential of pre-gestational intake of Laportea interrupta L. (L. interrupta) leaf decoction as an aid for fetal-maternal health by determining its influence on embryonic implantation and growth, placental labyrinth vasculo ...
Jeriz Anne S. de Guzman +3 more
doaj +1 more source
Aggressive Surveillance Is Needed to Detect Endoleaks and Junctional Separation between Device Components after Zenith Fenestrated Aortic Reconstruction [PDF]
, 2019 Background Junctional separation and resulting type IIIa endoleak is a well-known problem after EVAR (endovascular aneurysm repair). This complication results in sac pressurization, enlargement, and eventual rupture.
Dalsing, Michael C. +7 more
core +1 more source
Single-cell and spatial architecture of primary liver cancer
Communications Biology, 2023 Primary liver cancer (PLC) poses a leading threat to human health, and its treatment options are limited. Meanwhile, the investigation of homogeneity and heterogeneity among PLCs remains challenging.
Pei-Yun Zhou +24 more
doaj +1 more source
Modeling superimposed preeclampsia using Ang II (Angiotensin II) infusion in pregnant stroke-prone spontaneously hypertensive rats [PDF]
, 2018 Hypertensive disorders of pregnancy are the second leading cause of maternal deaths worldwide. Superimposed preeclampsia is an increasingly common problem and often associated with impaired placental perfusion. Understanding the underlying mechanisms and
Beattie, Elisabeth +7 more
core +2 more sources
Frontiers in Toxicology, 2023 The placenta plays a critical role in nutrient-waste exchange between the maternal and fetal circulations, thus functioning as an interface that profoundly impacts fetal growth and development. The placenta has long been considered an asexual organ, but,
Julie A. Griffith +19 more
doaj +1 more source
Acta Obstetricia et Gynecologica Scandinavica, 2018 Our aim was to correlate junctional zone thickening and irregularity (junctional zone disease) and other ultrasonographic features of adenomyosis with the histopathology of the endometrial‐myometrial junctional zone.
C. Rasmussen, E. Hansen, M. Dueholm
semanticscholar +1 more source
Cell Reports, 2017 Denudation of the ependyma due to loss of cell adhesion mediated by cadherin-based adherens junctions is a common feature of perinatal hydrocephalus. Junctional stability depends on the interaction between cadherins and the actin cytoskeleton.
Conor J. O’Leary +7 more
doaj +1 more source
Multigene Next-Generation Sequencing Panel Identifies Pathogenic Variants in Patients with Unknown Subtype of Epidermolysis Bullosa: Subclassification with Prognostic Implications [PDF]
, 2017 Purpose: Epidermolysis bullosa (EB), the prototype of heritable blistering diseases, is caused by mutations in as many as 19 distinct genes. In this study, we evaluated the molecular basis of EB in 93 families, many of them of unknown subtype. Methods:
Abiri, Maryam +15 more
core +1 more source