Results 241 to 250 of about 2,357,205 (332)

Redox‐aktivierte Sonden für Hochkontrastige Live‐Bildgebung Postsynaptischer Neuronaler Gerüste

open access: yesAngewandte Chemie, EarlyView.
Sylives sind modifizierte fluoreszierende Peptide für eine kontrastreiche Live‐Bildgebung inhibitorischer (Gephyrin) und exzitatorischer (PSD‐95) postsynaptischer Gerüststrukturen in nativen Neuronen. Eine saubere Markierung erfordert niedrige Sondenkonzentrationen im Nanomolarbereich, während die Aufnahme mikromolare Konzentrationen zellpenetrierender
Christiane Huhn   +10 more
wiley   +1 more source

Selbstassemblierte (Aza‐)BODIPY Farbstoffe für Biomedizinische In Vivo Bildgebung

open access: yesAngewandte Chemie, EarlyView.
Dieses Minireview klassifiziert (Aza‐)BODIPY‐Farbstoffe anhand ihrer molekularen Stapelungsmodi und Aggregattypen (H‐, oblique‐ oder J‐Typ) in wässrigen Medien und setzt diese Merkmale in Beziehung zu ihrer multimodalen Bildgebungsleistung. Durch die Verknüpfung von molekularem Design, Exzitonenkopplung und pfadabhängiger Assemblierung stellen wir ...
Antonia Albers   +2 more
wiley   +1 more source

Kribbia dieselivorans Jung et al. 2006

open access: green
J. Sarda Carbasse   +4 more
openalex   +1 more source

Helmeted hornbill cranial kinesis: Balancing mobility and stability in a high‐impact joint

open access: yesThe Anatomical Record, EarlyView.
Abstract Prokinesis—in which a craniofacial joint allows the rostrum to move relative to the braincase—is thought to confer diverse advantages in birds, mostly for feeding. A craniofacial joint would, however, be a weak link if cranial stability is important. Paradoxically, we have identified a craniofacial joint in helmeted hornbills (Rhinoplax vigil),
Mike Schindler   +8 more
wiley   +1 more source

Linezolid prevents fibroblast activation and ameliorates tissue fibrosis by inhibition of mitochondrial translation

open access: yesArthritis &Rheumatology, Accepted Article.
Background Beyond its role as a ribosome‐targeting antibiotic, linezolid was recently shown to modulate immune responses by inhibiting mitochondrial translation. Since mitochondrial dysfunction is implicated in various fibrotic diseases, including systemic sclerosis (SSc), this study aimed to evaluate the antifibrotic potential of linezolid and ...
Xuezhi Hong   +13 more
wiley   +1 more source

Molecular stratification of antiphospholipid syndrome through integrative analysis of the whole‐blood RNA transcriptome

open access: yesArthritis &Rheumatology, Accepted Article.
Objective Antiphospholipid syndrome (APS) is a thrombo‐inflammatory disorder characterized by clinical and mechanistic heterogeneity that complicates early diagnosis and hinders targeted treatment. We aimed to identify distinct molecular endotypes among antiphospholipid antibody (aPL)‐positive patients using whole‐blood transcriptomics.
Amala Ambati   +13 more
wiley   +1 more source

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