Results 241 to 250 of about 1,009,989 (332)

Severity of effect considerations regarding the use of mutation as a toxicological endpoint for risk assessment: A report from the 8th International Workshop on Genotoxicity Testing (IWGT)

open access: yesEnvironmental and Molecular Mutagenesis, EarlyView.
Abstract Exposure levels without appreciable human health risk may be determined by dividing a point of departure on a dose–response curve (e.g., benchmark dose) by a composite adjustment factor (AF). An “effect severity” AF (ESAF) is employed in some regulatory contexts.
Barbara L. Parsons   +17 more
wiley   +1 more source

Evaluation of the standard battery of in vitro genotoxicity tests to predict in vivo genotoxicity through mathematical modeling: A report from the 8th International Workshop on Genotoxicity Testing

open access: yesEnvironmental and Molecular Mutagenesis, EarlyView.
Abstract In human health risk assessment of chemicals and pharmaceuticals, identification of genotoxicity hazard usually starts with a standard battery of in vitro genotoxicity tests, which is needed to cover all genotoxicity endpoints. The individual tests included in the battery are not designed to pick up all endpoints.
Mirjam Luijten   +15 more
wiley   +1 more source

Policy entrepreneurship for transformative governance

open access: yesEuropean Policy Analysis, EarlyView.
Abstract Scholarship is growing on societal transitions, describing radical societal change involving multiple sectors and scales, and transformative governance, describing how public, private, and civil society actors use tools of policy to pursue this fundamental change, aiming to build resiliency and sustainability.
Gwen Arnold   +4 more
wiley   +1 more source

Constructing the “moralization shock”: The role of contingency in the translation of anticorruption policy in France

open access: yesEuropean Policy Analysis, EarlyView.
Abstract This article applies the concept of transaction to the process of policy transfer, through the case of conflict of interest regulation in France, using archives, documentary sources, and interviews with stakeholders. It contributes to the literature on policy translation by clarifying the role of contingency, which remains underspecified.
Sofia Wickberg
wiley   +1 more source

Differentiated policy implementation in food safety and animal welfare policymaking

open access: yesEuropean Policy Analysis, EarlyView.
Abstract Agri‐food policies are in the midst of far‐reaching transitions, including the transformation towards sustainable production and food consumption. The European Green Deal and Farm to Fork Strategy prioritize food safety and animal welfare issues, aiming to transform food systems towards more sustainability.
Giulia Bazzan, Colette S. Vogeler
wiley   +1 more source

Power Relations in the Preparation of the Nondiscrimination Act: The Controversial Issue of Supervising Discrimination in Working Life

open access: yesEuropean Policy Analysis, EarlyView.
ABSTRACT In the context of Europeanisation and neo‐corporatism, we examine the lengthy process of revising the Nondiscrimination Act in Finland, spanning from 2007 to 2023. The focus is on the mandate of the Nondiscrimination Ombudsman in the workplace and on explaining the sudden policy change of strengthening it after a prolonged standstill.
Laura Jauhola, Kati Rantala
wiley   +1 more source

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