Results 61 to 70 of about 164,028 (312)
Molecular Oncology, EarlyView.This study simultaneously investigated circulating tumor cells (CTCs) and exosomes from small‐cell lung cancer (SCLC) patients. The elevated expression of JUNB and CXCR4 in CTCs was a poor prognostic factor for SCLC patients, whereas exosomal overexpression of these biomarkers revealed a high discrimination ability of patients from healthy individuals,
Dimitrios Papakonstantinou +13 more
wiley +1 more source
Molecular Oncology, EarlyView.In molecular cancer diagnostics, comprehensive genomic profiling (CGP) is going to replace the small NGS panels since it provides all clinically relevant somatic variants as well as genomic biomarkers with clinical value. Here, we compared two CGP assays and demonstrate that the choice for diagnostic implementation will depend on the specific ...
Guy Froyen +17 more
wiley +1 more source
The Role of History in the Process of Jurisprudential Inference with the Emphasis on the Discovery of Tradition and Jurisprudential Decree [PDF]
تاریخ اسلامOne of the important areas of emerging jurisprudential debates is the investigation of the role of history in jurisprudence with an emphasis on questions about the how of discovering the tradition and the origin of issuing jurisprudential decree. In this
Seyied Mahdi Mohammadi
doaj +1 more source
Identification of inhibitors of the Salmonella FraB deglycase, a drug target
FEBS Open Bio, EarlyView.A high‐throughput screen was used to identify inhibitors of Salmonella FraB, a drug target. Characterization of top hits (identified after an additional counter screen) revealed that some triazolidines, thiadiazolidines, and triazolothiadiazoles are mixed‐type inhibitors of FraB.
Jamison D. Law +6 more
wiley +1 more source
A Survey of Decision Making in Adversarial Games [PDF]
arXiv, 2022 Game theory has by now found numerous applications in various fields, including economics, industry, jurisprudence, and artificial intelligence, where each player only cares about its own interest in a noncooperative or cooperative manner, but without obvious malice to other players. However, in many practical applications, such as poker, chess, evader
arxiv
On the Centrality of Jurisprudence [PDF]
The American Journal of Jurisprudence, 2019 Political communities typically organise themselves by an appeal to values. Sometimes the values invoked are abstract ideas such as justice or equality. One such idea is that of law. In many important instances, practices cannot be understood except by reference to the values to which they make an implicit appeal but from which they fall short; and ...
openaire +3 more sources
Knowledge Diffusion Process & Common Islamic Banking Governance Principles: Integrative Perspective (s) of Managers and Shariah Scholars [PDF]
arXiv, 2020 Islamic banks being commercial entities strive to earn profit within shariah ambit. Therefore, they seem to be basing themselves upon two knowledge streams namely i) Islamic jurisprudence principles, and ii) banking principles. Islamic jurisprudence principles primarily aim at bringing shariah compliance while banking principles focus profitability ...
arxiv
The Theory of Artificial Immutability: Protecting Algorithmic Groups Under Anti-Discrimination Law [PDF]
arXiv, 2022 Artificial Intelligence (AI) is increasingly used to make important decisions about people. While issues of AI bias and proxy discrimination are well explored, less focus has been paid to the harms created by profiling based on groups that do not map to or correlate with legally protected groups such as sex or ethnicity.
arxiv
Journal of Applied Clinical Medical Physics, EarlyView.Abstract Purpose This study compares the dosimetric accuracy of deep‐learning‐based MR synthetic CT (sCT) in brain radiotherapy between the Analytical Anisotropic Algorithm (AAA) and AcurosXB (AXB). Additionally, it proposes a novel metric to predict the dosimetric accuracy of sCT for individual post‐surgical brain cases.
Jeffrey C. F. Lui +3 more
wiley +1 more source
On Rational Jurisprudence: A Problem in Bayesian Confirmation Theory [PDF]
arXiv, 2022 This paper is concerned with the epistemic question of confirming a hypothesis -- the guilt of a defendant -- by way of testimony heard by a juror over the course of an American-style criminal trial. In it, I attempt to settle a dispute between two strands of the legal community over the issue of whether the methods of Bayesian rationality are ...
arxiv