Results 221 to 230 of about 74,947 (289)

Innate Immune Reprogramming Mediated by Endogenous Retroelement Dysregulation Drives Multiple Sclerosis Progression

Annals of Clinical and Translational Neurology, EarlyView.
Epigenetic reprogramming in hematopoietic stem and progenitor cells (HSPCs) and downstream myeloid cells, mediated by H3.3 downregulation and endogenous retroelement (ERE) overexpression, contributes to the progression of multiple sclerosis (MS). ABSTRACT Background Skewed myelopoiesis in the bone marrow has been identified as a key driver of multiple ...
Li‐Mei Xiao, Qiu‐Ping Zhao, Run‐Yun Li, Wei Chen, Huan‐Huan Song, Wan‐Jin Chen, Ying Fu   +6 more
wiley   +1 more source

Chronology of H3N2 human influenza virus surface glycoprotein adaptation from 1968 to 2019 reveals a surge of adaptation between 1997 and 2002. [PDF]

J Virol
Lei H, Xiao B, Lin X, Liang Z, Ling S, Bai Y, Dhanasekaran V, Song W, Wong S-S, Zanin M.   +9 more
europepmc   +1 more source

Paramagnetic Rim Lesions Are Associated With Trans‐Synaptic Degeneration of the Visual Pathway in Multiple Sclerosis

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objectives Retrograde trans‐synaptic degeneration (rTSD) from posterior visual pathway lesions in multiple sclerosis (MS) is characterized by hemi‐macular ganglion cell‐inner plexiform layer (GCIPL) thinning and contralateral visual field loss.
Abdul Jaber Tayem, Angel Liu, Sargis Manukyan, Mustafa Subhi, Elaina Luskin, Bryan Quah, Sreekanth Madhusoodhanan Nair, Arzu C. Has Silemek, Gabriela Zabala, Yujie Cui, Laura Locke, Paula Barreras, Marwa Kaisey, Vinicius Calsavara, Daniel S. Reich, Nancy L. Sicotte, Pascal Sati, Omar Al‐Louzi   +17 more
wiley   +1 more source

Exploring Consent to Use Real-World Data in Lung Cancer Radiotherapy: Decision of a Citizens' Jury for an 'Informed Opt-Out' Approach. [PDF]

Health Care Anal
Kapadi A, Turner-Uaandja H, Holley R, Wicks K, Hamrang L, Turner B, van Staa T, Bowden C, Keane A, Price G, Faivre-Finn C, French D, Sanders C, Holm S, Devaney S.   +14 more
europepmc   +1 more source

Setting Primary Health and Social Care Priorities Using a Deliberative Democratic Participatory Approach. [PDF]

Health Expect
Wales C, Abbott P, Street J, Fawcett L, Jennings M, Sharp W, Lee P.   +6 more
europepmc   +1 more source

Spatially resolved transcriptomic profiling identifies distinct signatures in parenchymal and vascular microenvironments in Alzheimer's Disease with Cerebral Amyloid Angiopathy. [PDF]

Alzheimers Dement
Chimal-Juárez E, Jury-Garfe N, Gomez-Isaza L, Troncoso JC, Lasagna-Reeves CA.   +4 more
europepmc   +1 more source

Subdural hematomas and medical malpractice in the USA: an analysis of 314 patients. [PDF]

Trauma Surg Acute Care Open
Pecorari IL, Ghosh S, Lally A, Agarwal V.   +3 more
europepmc   +1 more source

Microbial living materials promote coral larval settlement. [PDF]

PNAS Nexus
Levy N, Kundu S, Freckelton M, Dinasquet J, Flores I, Galindo-Martínez CT, Tresguerres M, De La Garza V, Sun Y, Karimi Z, Drury C, Jury CP, Hancock JR, Chen S, Hadfield MG, R3D Consortium , Wangpraseurt D.   +16 more
europepmc   +1 more source