Results 51 to 60 of about 719,976 (345)

The Caenorhabditis elegans DPF‐3 and human DPP4 have tripeptidyl peptidase activity

FEBS Letters, EarlyView.
The dipeptidyl peptidase IV (DPPIV) family comprises serine proteases classically defined by their ability to remove dipeptides from the N‐termini of substrates, a feature that gave the family its name. Here, we report the discovery of a previously unrecognized tripeptidyl peptidase activity in DPPIV family members from two different species.
Aditya Trivedi, Rajani Kanth Gudipati
wiley   +1 more source

Real‐time assay of ribonucleotide reductase activity with a fluorescent RNA aptamer

FEBS Letters, EarlyView.
Ribonucleotide reductases (RNR) synthesize DNA building blocks de novo, making them crucial in DNA replication and drug targeting. FLARE introduces the first single‐tube real‐time coupled RNR assay, which enables isothermal tracking of RNR activity at nanomolar enzyme levels and allows the reconstruction of allosteric regulatory patterns and rapid ...
Jacopo De Capitani, Noemi E. Nwosu, Viktoria Gocke, Müge Kasanmascheff, Hannes Mutschler   +4 more
wiley   +1 more source

Function‐driven design of a surrogate interleukin‐2 receptor ligand

FEBS Letters, EarlyView.
Interleukin (IL)‐2 signaling can be achieved and precisely fine‐tuned through the affinity, distance, and orientation of the heterodimeric receptors with their ligands. We designed a biased IL‐2 surrogate ligand that selectively promotes effector T and natural killer cell activation and differentiation. Interleukin (IL) receptors play a pivotal role in
Ziwei Tang, Zelin Cheng, Teng Li, Fulian Wang, Liangminghui Zhang, Xiuxiu He, Lili Liu, Wei Wang, Aibin Liang, Guang Yang   +9 more
wiley   +1 more source

Le délibéré aux assises, ultime point aveugle dans l’affaire d’Outreau

Droit et Cultures, 2008
This article deals with the deliberations in the Cour d’assises in the Outreau case, both in the first resort and in appeal, by using the hearings before the Parliamentary investigation committee and the author’s professional experience as a judge (17 ...
Jean-Marie Fayol-Noireterre
doaj  

An upstream open reading frame regulates expression of the mitochondrial protein Slm35 and mitophagy flux

FEBS Letters, EarlyView.
This study reveals how the mitochondrial protein Slm35 is regulated in Saccharomyces cerevisiae. The authors identify stress‐responsive DNA elements and two upstream open reading frames (uORFs) in the 5′ untranslated region of SLM35. One uORF restricts translation, and its mutation increases Slm35 protein levels and mitophagy.
Hernán Romo‐Casanueva, Ariann E. Mendoza‐Martínez, P. Abril Medina‐Flores, Carlos Campero‐Basaldua, Alexander DeLuna, Soledad Funes   +5 more
wiley   +1 more source

Internal factors affecting the jury members verdict

Психология и право, 2013
The article is devoted to the analysis of socio-demographic and individual psychological characteristics that influence the verdict of jury. The study involved 38 men and women aged 25 to 64 years. With the help of a questionnaire, developed on the basis
Kalashnikova A.S., Levochkina N.S.
doaj  

Criminal Trial Juries in Australia: From Penal Colonies to a Federal Democracy [PDF]

, 1999
The recent history of juries in Australia reveals an interesting clash between the endeavours of state and territory governments to reduce the costs associated with jury trial by various means and the determination of the High Court of Australia to ...
Chesterman, Michael
core   +1 more source

In situ molecular organization and heterogeneity of the Legionella Dot/Icm T4SS

FEBS Letters, EarlyView.
We present a nearly complete in situ model of the Legionella Dot/Icm type IV secretion system, revealing its central secretion channel and identifying new components. Using cryo‐electron tomography with AI‐based modeling, our work highlights the structure, variability, and mechanism of this complex nanomachine, advancing understanding of bacterial ...
Przemysław Dutka, Yuxi Liu, Stefano Maggi, Debnath Ghosal, Jue Wang, Prashant P. Damke, Stephen D. Carter, Wei Zhao, Sukhithasri Vijayrajratnam, Joseph P. Vogel, Carrie L. Shaffer, Grant J. Jensen   +11 more
wiley   +1 more source

CALL Video & Filmtage 2023: Filmfestival des jungen Kurzfilms vom 05. bis 09. Oktober 2023

Medienimpulse, 2023
Die Video & Filmtage – das Festival des jungen Kurzfilms richtet sich an Filmemacher_innen bis 22 Jahre. Das Medienzentrum als Veranstalter bietet im Vorfeld Beratung und Workshops, sowie Studio- und Schnittplätze als auch Equipmentverleih an, um ...
Katharina Kaiser-Müller
doaj  

The Impact of Ulcerative Colitis on Colorectal Cancer Prognosis: The Jury is Still Out [PDF]

, 2022
Arielle E. Kanters, David Liska
openalex   +1 more source