Results 101 to 110 of about 632,340 (320)

In vivo magnetic resonance imaging of orthotopic prostate cancer

open access: yesBioTechniques, 2020
Methods for imaging orthotopic prostate tumors within the prostate or small tumors with extension outside the prostate are needed to more closely model human prostate tumors, which are most commonly located within the gland or may extend just through the
Murali K Ravoori   +7 more
doaj   +1 more source

Perspectives in educating molecular pathologists on liquid biopsy: Toward integrative, equitable, and decentralized precision oncology

open access: yesMolecular Oncology, EarlyView.
Liquid biopsy enables minimally invasive, real‐time molecular profiling through analysis of circulating biomarkers in biological fluids. This Perspective highlights the importance of training pathologists through integrative educational programs, such as the European Masters in Molecular Pathology, to ensure effective and equitable implementation of ...
Marius Ilié   +13 more
wiley   +1 more source

Dynamic Clusters [PDF]

open access: yes
Globalization has had an enormous impact on traditional industrial structures. It seems almost the case that everything is everywhere the same. And yet, in reality, some regions in a single industrialized country enjoy rapid economic growth while others ...
Oliver Falck, Stephan Heblich
core  

Urban Logistics and Transportation - Defining a B2B Concept of Operations for Urban Construction Consolidation Centres [PDF]

open access: yes, 2012
The challenges facing the UK construction industry reflect many inefficiencies in current practice: 60% of planned vehicle deliveries do not arrive on time.
Harrington, Tomás Seosamh   +1 more
core  

Transcriptional network analysis of PTEN‐protein‐deficient prostate tumors reveals robust stromal reprogramming and signs of senescent paracrine communication

open access: yesMolecular Oncology, EarlyView.
Combining PTEN protein assessment and transcriptomic profiling of prostate tumors, we uncovered a network enriched in senescence and extracellular matrix (ECM) programs associated with PTEN loss and conserved in a mouse model. We show that PTEN‐deficient cells trigger paracrine remodeling of the surrounding stroma and this information could help ...
Ivana Rondon‐Lorefice   +16 more
wiley   +1 more source

The impact of inter-organizational management control systems on performance: a longitudinal case study of a supplier relation in automotive. [PDF]

open access: yes
This study investigates whether appropriate management control design of supplier relations is associated with better performance. Although management control systems (MCSs) are found to be contingent on situational characteristics, it remains unclear ...
Pernot, Eli, Roodhooft, Filip
core  

Supplier's capabilites and its influence on competitive advantage in automotive industry [PDF]

open access: yes, 2014
In an increasingly competitive market place, manufacturers need to provide higher quality products at cheaper price and faster delivery. Besides that, rapid technology changes require greater supplier capabilities and more active manufacturer-supplier ...
Abdul Hamid, Abu Bakar   +2 more
core  

Just-in-time: Gaze guidance in natural behavior.

open access: yesPLoS Computational Biology
Natural eye movements have primarily been studied for over-learned activities such as tea-making, sandwich-making, and hand-washing, which have a fixed sequence of associated actions.
Ashima Keshava   +5 more
doaj   +1 more source

STIM1 activation is regulated by a 14 amino acid sequence adjacent to the CRAC activation domain

open access: yesAIMS Biophysics, 2016
Oligomerization of the Ca2+ sensor, STIM1, in the endoplasmic reticulum (ER) membrane, caused by depletion of ER Ca2+ stores, results in STIM1 coupling to the plasma membrane Ca2+ channel protein, Orai1, to activate Ca2+ influx in a process known as ...
Marek K. Korzeniowski   +2 more
doaj   +1 more source

Potential therapeutic targeting of BKCa channels in glioblastoma treatment

open access: yesMolecular Oncology, EarlyView.
This review summarizes current insights into the role of BKCa and mitoBKCa channels in glioblastoma biology, their potential classification as oncochannels, and the emerging pharmacological strategies targeting these channels, emphasizing the translational challenges in developing BKCa‐directed therapies for glioblastoma treatment.
Kamila Maliszewska‐Olejniczak   +4 more
wiley   +1 more source

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