Results 121 to 130 of about 632,340 (320)

Infrared laser sampling of low volumes combined with shotgun lipidomics reveals lipid markers in palatine tonsil carcinoma

Molecular Oncology, EarlyView.
Nanosecond infrared laser (NIRL) low‐volume sampling combined with shotgun lipidomics uncovers distinct lipidome alterations in oropharyngeal squamous cell carcinoma (OPSCC) of the palatine tonsil. Several lipid species consistently differentiate tumor from healthy tissue, highlighting their potential as diagnostic markers.
Leonard Kerkhoff, Manuela Moritz, Dennis Eggert, Anna Worthmann, Joerg Heeren, Henrike Zech, Till S. Clauditz, Waldemar Wilczak, Hartmut Schlüter, Christian S. Betz, Arne Böttcher, Jan Hahn   +11 more
wiley   +1 more source

Between Internationalisation and Proximity: the internationalisation process of automotive first tier suppliers [PDF]

The paper analyses the strategies of internationalization pursued by first tier automotive suppliers (FTS). The advent of modular production in this sector implies many changes in vertical relationships, which can in turn be used to explain the causes ...
Vincent FRIGANT (GREThA)
core  

Smart City Supply – Verkehrstechnologien, Güterversorgung und Stadtentwicklung auf dem Weg ins 4.0-Zeitalter [PDF]

, 2017
Der Planungsansatz Smart City Supply zielt auf die Aussichten, Voraussetzungen und Möglichkeiten für eine Umstellung der Güterversorgung städtischer Siedlungsräume auf eine nachhaltige postfossile Gütermobilität ab, die Null-Emissionen in der urbanen ...
Dörr, Heinz, Marsch, Viktoria, Toifl, Yvonne   +2 more
core  

Peak Height Pattern in Dichloro-Rhodamine and Energy Transfer Dye Terminator Sequencing

BioTechniques, 1998
Establishing the pattern in peak heights within local sequence contexts improves the accuracy of base calling and the identification of DNA sequence variations in dye-terminator cycle sequencing.
H. Zakeri, G. Amparo, S.-M. Chen, S. Spurgeon, P.-Y. Kwok   +4 more
doaj   +1 more source

Recurrent cancer‐associated ERBB4 mutations are transforming and confer resistance to targeted therapies

Molecular Oncology, EarlyView.
We show that the majority of the 18 analyzed recurrent cancer‐associated ERBB4 mutations are transforming. The most potent mutations are activating, co‐operate with other ERBB receptors, and are sensitive to pan‐ERBB inhibitors. Activating ERBB4 mutations also promote therapy resistance in EGFR‐mutant lung cancer.
Veera K. Ojala, Sini Ahonen, Sara Peltola, Aura Tuohisto‐Kokko, Olaya Esparta, Peppi Suominen, Anne Jokilammi, Iman Farahani, Deepankar Chakroborty, Nikol Dibus, Steffen Boettcher, Tomi T. Airenne, Mark S. Johnson, Lisa D. Eli, Klaus Elenius, Kari J. Kurppa   +15 more
wiley   +1 more source

Peroxidasin enables melanoma immune escape by inhibiting natural killer cell cytotoxicity

Molecular Oncology, EarlyView.
Peroxidasin (PXDN) is secreted by melanoma cells and binds the NK cell receptor NKG2D, thereby suppressing NK cell activation and cytotoxicity. PXDN depletion restores NKG2D signaling and enables effective NK cell–mediated melanoma killing. These findings identify PXDN as a previously unrecognized immune evasion factor and a potential target to improve
Hsu‐Min Sung, David Bickel, Lena C. M. Krause, Daria Ezeriņa, Christian Ickes, Julian Wojtachnia, Christine S. Gibhardt, Magdalena Shumanska, Khadija Wahni, Andrea Paluschkiwitz, Julia Malo Pueyo, Ekaterina Baranova, Wim Vranken, Hedwig Stanisz, Ioana Stejerean‐Todoran, Michael P. Schön, Joris Messens, Ivan Bogeski   +17 more
wiley   +1 more source

Correlation of the differential expression of PIK3R1 and its spliced variant, p55α, in pan‐cancer

Molecular Oncology, EarlyView.
PIK3R1 undergoes alternative splicing to generate the isoforms, p85α and p55α. By combining large patient datasets with laboratory experiments, we show that PIK3R1 spliced variants shape cancer behavior. While tumors lose the protective p85α isoform, p55α is overexpressed, changes linked to poorer survival and more pronounced in African American ...
Ishita Gupta, Yang Song, Madeleine Ndahayo, Anirudh Saxena, Theresa Guo, Dylan Z. Kelley, Jessica Gore, Andrew Hennigan, Alexa Anderson, John C. Papadimitriou, Daria A. Gaykalova   +10 more
wiley   +1 more source

Just-in-sequence ellátási stratégiák [PDF]

, 2013
The increased customer-orientation of production companies leaded to the growth of complexity of manufacturing and connected logistics processes. To be winners of today’s market situation manufacturing companies try to increase their flexibility to ...
Bányai, Tamás
core   +1 more source

Visual Management in production management: a literature synthesis [PDF]

, 2016
Purpose- The purpose of this paper is to holistically discuss, explore and synthesise the key literature on Visual Management, an important, yet highly fragmented subject that is frequently referred in lean production accounts. Research Methodology - An
Algan Tezel, Lauri Koskela, Nikkan Kogyo Shimbun, Patricia Tzortzopoulos   +3 more
core   +2 more sources

Variability of the aspA Genes in Yersinia pestis Strains of the Main and Non-Main Subspecies

Проблемы особо опасных инфекций, 2009
Demonstrated was variability of the aspA gene nucleotide sequence in Yersinia pestis strains of the main and non-main subspecies isolated in the Russian Federation and neighboring countries.
G. A. Eroshenko, G. N. Odinokov, Ya. M. Krasnov, N. P. Gooseva, V. V. Kutyrev   +4 more
doaj   +1 more source