Results 161 to 170 of about 632,340 (320)
FEBS Open Bio, EarlyView.Mouse pre‐implantation development involves a transition from totipotency to pluripotency. Integrating transcriptomics, epigenetic profiling, low‐input proteomics and functional assays, we show that eight‐cell embryos retain residual totipotency features, whereas cytoskeletal remodeling regulated by the ubiquitin‐proteasome system drives progression ...
Wanqiong Li +8 more
wiley +1 more source
It's all in Marshall: the impact of external economies on regional dynamics [PDF]
, 2007 Marshall's student Pigou noted: It's all in Marshall. From a static point of view, this seems rather bold in a constantly changing world. However, this statement becomes more plausible in a dynamic context, where principles are subject to change ...
Audretsch, David B. +2 more
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Nuclear pore links Fob1‐dependent rDNA damage relocation to lifespan control
FEBS Open Bio, EarlyView.Damaged rDNA accumulates at a specific perinuclear interface that couples nucleolar escape with nuclear envelope association. Nuclear pores at this site help inhibit Fob1‐induced rDNA instability. This spatial organization of damage handling supports a functional link between nuclear architecture, rDNA stability, and replicative lifespan in yeast.
Yamato Okada +5 more
wiley +1 more source
The Car Resequencing Problem with Pull-Off Tables [PDF]
The car sequencing problem determines sequences of different car models launched down a mixed-model assembly line. To avoid work overloads of workforce, car sequencing restricts the maximum occurrence of labor-intensive options, e.g., a sunroof, by ...
Franz Rothlauf, Nils Boysen, Uli Golle
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Технології менеджменту знань і відкрите співробітництво [PDF]
, 2017 Розкрито основи дисципліни «Технології менеджменту знань», зокрема базу менеджменту знань і технологій управління знаннями, початки інженерії знань. Наведено приклади практичної реалізації функцій менеджменту знань в аспекті відкритого співробітництва ...
Fedoniuk, Serhii V. +1 more
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OS BENEFÍCIOS DA IMPLEMENTAÇÃO DO JUST-IN-SEQUENCE NAS ORGANIZAÇÕES
Revista SODEBRAS, 2020 P. F. A. REIS +3 more
openaire +1 more source
FEBS Open Bio, EarlyView.Time‐resolved X‐ray solution scattering captures how proteins change shape in real time under near‐native conditions. This article presents a practical workflow for light‐triggered TR‐XSS experiments, from data collection to structural refinement. Using a calcium‐transporting membrane protein as an example, the approach can be broadly applied to study ...
Fatemeh Sabzian‐Molaei +3 more
wiley +1 more source
Promiscuous stimulation of HSP70 ATPase activity by parasite‐derived J‐domains
FEBS Open Bio, EarlyView.The malaria parasite Plasmodium falciparum exports three highly homologous yet functionally divergent J‐domain proteins into human erythrocytes. Here, we show that J‐domains isolated from all three proteins effectively stimulate the ATPase activity of both endogenous host and exported parasite HSP70 chaperones.
Julian Barth +6 more
wiley +1 more source
Aging and Cancer, EarlyView.Natural products target the aging kidney in diabetic nephropathy by restoring the AMPK–SIRT1–Nrf2 axis, reducing oxidative stress, inflammation, fibrosis, and cellular senescence while enhancing mitochondrial biogenesis and antioxidant defenses.
Sherif Hamidu +8 more
wiley +1 more source
, 2013 When thinking of overseas business expansion, most think of China. This is for good reason: China commands a lion’s share of foreign direct investment money.
Briscoe, Theodore W., III
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