Functional and structural segregation of overlapping helices in HIV-1
Overlapping coding regions balance selective forces between multiple genes. One possible division of nucleotide sequence is that the predominant selective force on a particular nucleotide can be attributed to just one gene.
Maliheh Safari +6 more
doaj +1 more source
Optimization of Just-In-Sequence Supply: A Flower Pollination Algorithm-Based Approach [PDF]
The just-in-sequence inventory strategy, as an important part of the supply chain solutions in the automotive industry, is based on feedback information from the manufacturer. The performance, reliability, availability and cost efficiency are based on the parameters of the members of the supply chain process.
Tamás Bányai +5 more
openaire +1 more source
Capturing the primordial Kras mutation initiating urethane carcinogenesis
Why the carcinogen urethane causes only lung tumours driven by a specific oncogenic mutation in just one Ras gene in mice is unclear. Here, the authors capture mutations immediately after urethane exposure and show that the sequence specificity of ...
Siqi Li +2 more
doaj +1 more source
Bayesian model of protein primary sequence for secondary structure prediction. [PDF]
Determining the primary structure (i.e., amino acid sequence) of a protein has become cheaper, faster, and more accurate. Higher order protein structure provides insight into a protein's function in the cell. Understanding a protein's secondary structure
Qiwei Li +4 more
doaj +1 more source
Use of a PNA probe to block DNA-mediated PCR product formation in prokaryotic RT-PCR
A novel method eliminating DNA-mediated PCR product formation in reverse transcription PCR (RT-PCR) amplification of specific RNA sequences is described. The method exploits the higher melting temperature values of peptide nucleic acid (PNA)/DNA duplexes
Mikkel Bender +3 more
doaj +1 more source
Multiplexing Genetic and Nucleosome Positioning Codes: A Computational Approach. [PDF]
Eukaryotic DNA is strongly bent inside fundamental packaging units: the nucleosomes. It is known that their positions are strongly influenced by the mechanical properties of the underlying DNA sequence.
Behrouz Eslami-Mossallam +4 more
doaj +1 more source
Controlling just-in-sequence flow-production
Analyses of the customer-order process in the automotive industry show that the vision of perfectly synchronized material flows in complex industrial production and logistics environments is still far from having become reality. The traditional strategy of maintaining high safety stock levels to counter the effects of ever more variety and uncertainty ...
openaire +1 more source
Modelling oscillations in the supply chain: the case of a just-in-sequence supply process from the automotive industry [PDF]
Abstract Pervasive and ubiquitous oscillations, mapping the repetitive variation in time of a specific state, are well known as abundant phenomena in research and practice. Motivated by the success of oscillators in the modelling, analysis and control of dynamical systems, we developed a related approach for the dynamic description of
openaire +2 more sources
Random sequences rapidly evolve into de novo promoters
Bacterial promoters initiate gene transcription and have distinct sequence features. Here, the authors show that random sequences that contain no information are just on the verge of functioning as promoters in Escherichia coli.
Avihu H. Yona, Eric J. Alm, Jeff Gore
doaj +1 more source
IMPROVING “JUST-IN-TIME, JUST-IN-SEQUENCE” DELIVERY IN FIRST-TIER SUPPLIERS
This paper presents an action-research project aiming at improving the performance of “just-in-time, just-in-sequence” auto parts manufacturing and delivery in three tier-1 suppliers of the Nissan plant in Barcelona. This research was conducted at the Barcelona School of Engineering (ETSEIB) and promoted by the Nissan factory in Barcelona.
Bautista Valhondo, Joaquín +1 more
openaire +6 more sources

