Results 71 to 80 of about 608,636 (263)
Molecular Oncology, EarlyView.RNA profiling of circulating extracellular vesicles (EVs) from blood samples of men undergoing prostate biopsy identifies transcripts associated with clinically significant prostate cancer. Integrative analysis with public tumor datasets links EV‐derived gene signatures to tumor stage and progression‐free survival, highlighting CASP3, XRCC2, and RIT1 ...
Stefan Werner +14 more
wiley +1 more source
Inter/intra-frame constrained vascular segmentation in X-ray angiographic image sequence
BMC Medical Informatics and Decision Making, 2019 Background Automatic vascular segmentation in X-ray angiographic image sequence is of crucial interest, for instance, for better quantifying coronary arteries in diagnostic and interventional procedures.
Shuang Song +7 more
doaj +1 more source
Frontiers in Microbiology, 2015 The rapid expansion of new sequencing technologies has enabled large-scale functional exploration of numerous microbial ecosystems, by establishing catalogues of functional genes and by comparing their prevalence in various microbiota.
Lisa eUfarté +2 more
doaj +1 more source
Molecular Oncology, EarlyView.Intratumour heterogeneity complicates precision management of advanced endometrial cancer. Circulating tumor DNA (ctDNA) offers a minimally invasive strategy to capture tumor evolution and therapeutic resistance. Here, we compare tumor‐agnostic NGS with tumor‐informed ddPCR, outlining their relative sensitivity, concordance, and clinical implications ...
Carlos Casas‐Arozamena +15 more
wiley +1 more source
Mitochondrial DNA. Part B. Resources, 2017 The complete chloroplast (cp) genome sequence of Rheum wittrockii, an endangered and medicinal plant of Kazakhstan, was firstly determined in the present study.
Shynar S. Dagarova +3 more
doaj +1 more source
preAssemble: a tool for automatic sequencer trace data processing
BMC Bioinformatics, 2006 Background Trace or chromatogram files (raw data) are produced by automatic nucleic acid sequencing equipment or sequencers. Each file contains information which can be interpreted by specialised software to reveal the sequence (base calling).
Laerdahl Jon K +2 more
doaj +1 more source
Molecular Oncology, EarlyView.Dormant cancer cells can hide in distant organs for years, evading treatment and the immune system. This review highlights how signals from the surrounding tissue and immune environment keep these cells inactive or trigger their reawakening. Understanding these mechanisms may help develop therapies to eliminate or control dormant cells and prevent ...
Kanishka Tiwary +1 more
wiley +1 more source
Peak Height Pattern in Dichloro-Rhodamine and Energy Transfer Dye Terminator Sequencing
BioTechniques, 1998 Establishing the pattern in peak heights within local sequence contexts improves the accuracy of base calling and the identification of DNA sequence variations in dye-terminator cycle sequencing.
H. Zakeri +4 more
doaj +1 more source
Molecular Oncology, EarlyView.This study shows that lung adenocarcinomas exploit developmental branching morphogenesis to acquire a therapy resistant basal‐like tumour cell state. This process was found to be regulated by combined TP53 loss‐of‐function and type‐I interferon signalling, identifying a novel axis for biomarker and therapeutic target discovery.
Kamila J Bienkowska +13 more
wiley +1 more source
Improving “just-in-time, just-in-sequence” delivery in first-tier suppliers
, 2015 This research was conducted at the Barcelona School of Engineering (ETSEIB) and promoted by the Nissan factory in Barcelona. In this paper, first, the concept of synchronous manufacturing is explored. After several improvement ideas are spotted within the Nissan plant, the paper focuses on the suppliers. An intervention approach is proposed.
Bautista Valhondo, Joaquín +1 more
openaire +2 more sources