Results 71 to 80 of about 2,033,952 (257)

A Comparative Study of Commit Representations for JIT Vulnerability Prediction

Computers
With the evolution of software systems, their size and complexity are rising rapidly. Identifying vulnerabilities as early as possible is crucial for ensuring high software quality and security.
Tamás Aladics, Péter Hegedűs, Rudolf Ferenc   +2 more
doaj   +1 more source

Elevated Process Model of Financial Performance on the Basis of Just In Time, Agile and Total Quality Management [PDF]

مطالعات مدیریت راهبردی, 2016
The aim of this research is designing the elevated process model of financial performance on the basis of Just In Time, agile and total quality management.
Belghis Bavarsad, Somayeh Ganjali, Farajallah Rahimi, Ali Mehrabi   +3 more
doaj  

Beam search filtrado com inserção de ociosidade na programação de uma máquina em ambiente do tipo jit Filtered beam search with ociosity insertion for single machine scheduling in a jit environment

Gestão & Produção, 1998
Este trabalho avalia a utilização do beam search filtrado (BSF) combinado com um algoritmo de inserção de ociosidade (AIO). O caso estudado é baseado em uma única máquina, com datas de entrega múltiplas e com penalidades distintas de adiantamento e de ...
Emerson Carlos Colin
doaj   +1 more source

Reconstructing enzyme evolution by protein engineering

FEBS Letters, EarlyView.
Natural enzyme evolution can be retraced by protein engineering methods such as directed evolution, rational design, and ancestral sequence reconstruction. These approaches reveal how enzymes emerged from ligand‐binding scaffolds, developed varying substrate preferences, formed oligomeric complexes, adapted to environmental changes, and evolved novel ...
Lukas Drexler, Markus R. Busch, Reinhard Sterner   +2 more
wiley   +1 more source

Decoding the dynamic extracellular matrix in cancer—3D models and bioscaffolds rewire the rules of tumor progression

FEBS Letters, EarlyView.
Cancer progression is regulated by the dynamic matrix code of the tumor microenvironment, which influences cellular behavior and disease development. Importantly, matrix remodeling in three‐dimensional cancer models more accurately reflects in vivo conditions compared to conventional two‐dimensional systems.
Sylvia Mangani, Konstantinos Spanopoulos, Zoi Piperigkou, Nikos K. Karamanos   +3 more
wiley   +1 more source

A Comparative study of DNA Alignment Algorithms and Boosting Performance Using Different Compilation Strategies

Cumhuriyet Science Journal
With the development of next generation sequencing technologies, the requirement of higher performance from DNA and Protein sequence alignment algorithms has become even greater.
Osman Doluca
doaj   +1 more source

A Comparative Study of the Components of Just in Time Production in Diverse Groups of Industries in Tabriz by Using Multivariate ANOVA [PDF]

مدیریت بهره وری, 2014
Just in time (JIT) production is a new approach and way of thinking in the management of industrial organizations, the principles and methods of which seek the complete and comprehensive elimination of wastage and the enhancement of productivity in all ...
MohammadAli Motafaker azad, Mehdi Allah verdi zadeh, Gholamreza SoltaniFesgendis, Mehdi Pourmogadam   +3 more
doaj  

Identification of a Shiga toxin A‐derived peptide internalized into Gb3 receptor‐bearing cells via interaction with the Shiga toxin B subunit

FEBS Letters, EarlyView.
The process of internalization of the Shiga toxin A subunit via formation of a complex with the Shiga toxin B subunit, which specifically binds to the Gb3 receptor. The peptide is designed to act as a carrier of drugs into cancer cells. Here, we explored the potential of peptides derived from the catalytic A subunit of Shiga toxin (STxA) to be drug ...
Giulia Opassi, João C. Encarnação, Valeria Napolitano, Grzegorz Dubin, Grzegorz Popowicz, Karl Andersson, U. Helena Danielson   +6 more
wiley   +1 more source

Investigating transcription factor dynamics in health and disease using FRAP

FEBS Letters, EarlyView.
FRAP analysis of GFP‐tagged transcription factors reveals how molecular mobility and target engagement change in response to drug treatment. By combining live‐cell imaging, quantitative model fitting, and statistical analysis, this approach uncovers transcription factor dynamics linked to disease mechanisms, providing a powerful framework for ...
Kannan Govindaraj, Carolina Vazquez Garzon, Jose Joaquin Velasco, Janine N. Post   +3 more
wiley   +1 more source

Microbiome‐blood–brain barrier interactions in aging — mechanisms and therapeutic potential

FEBS Letters, EarlyView.
Aging reshapes the gut microbiome (↓SCFA‐producing commensals; ↑pro‐inflammatory outputs), shifting circulating metabolites (↓SCFAs; ↑LPS, ↑TMAO, ↑PAA) that act at the BBB to increase nonspecific transcytosis, alter transport, and promote astrocyte reactivity, heightening brain vulnerability.
Daniel Cuervo‐Zanatta, Hari Baskar Balasubramanian, Amir Pasokh, Marietta Zille   +3 more
wiley   +1 more source