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AI‐Based D‐Amino Acid Substitution for Optimizing Antimicrobial Peptides to Treat Multidrug‐Resistant Bacterial Infection

open access: yesAdvanced Science, EarlyView.
This study constructed the first D‐amino acid antimicrobial peptide dataset and developed an AI model for efficient screening of substitution sites, with 80% of candidate peptides showing enhanced activity. The lead peptide dR2‐1 demonstrated potent antimicrobial activity in vitro and in vivo, high stability, and low toxicity.
Yinuo Zhao   +14 more
wiley   +1 more source

Just in Time Teaching

American Journal of Physics, 1999
Just-in-Time Teaching (JiTT) is an innovative method that enables faculty to increase interactivity in the classroom and engage students in learning. By creating a feedback loop between students' work at home and the classroom setting, time on task is improved in both quality and quantity. This paper includes an introduction to JiTT and evidence of its
Gregor M. Novak   +4 more
openaire   +1 more source

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