Results 31 to 40 of about 155,494 (257)

From mice to humans—divergent strategies for intestinal homeostasis and regeneration

FEBS Letters, EarlyView.
Recent advances such as organoid genome editing, xenotransplantation, imaging, and whole‐genome sequencing have enabled direct studies of human intestinal stem cells (ISCs). These studies reveal species‐specific features, including slower ISC proliferation, distinct injury responses, slower somatic mutation accumulation in humans, and an inverse ...
Keiko Ishikawa, Shinya Sugimoto, Toshiro Sato   +2 more
wiley   +1 more source

A Just Energy Transition Through the lens of Third World Approaches in International Law

Opolskie Studia Administracyjno-Prawne, 2023
The transition to green energy requires an all-hands-on-deck approach because of the effects of climate change on all. However, the nature and type of commitment or responsibilities required towards the transition are to be differentiated due to ...
LOVE ALFRED
doaj   +1 more source

Three phosphatase families form a community: The phosphohydrolases that act upon inositol pyrophosphates

FEBS Letters, EarlyView.
Inositol pyrophosphates are energy‐rich signaling molecules that perform critical functions in cells. Three different families of phosphatases hydrolyze the β phosphate of the inositol pyrophosphate molecules: two have narrow specificities and one is promiscuous.
Ronda J. Rolfes
wiley   +1 more source

Just Transition in National Climate Policy: Evidence from the Latest Nationally Determined Contributions

Chinese Journal of Urban and Environmental Studies
Despite the growing prominence of just transition in international climate discourse, little is known about how countries translate this concept into national policies.
Lu LU, Puran DOU, Weiqi ZHOU
doaj   +1 more source

Modelling stem cell differentiation related processes—A practical overview for biologists

FEBS Letters, EarlyView.
Stem cell differentiation is complex and difficult to control experimentally. This review introduces suitable computational modelling approaches that can support stem cell research, from mechanistic ODE and abstract models to multiscale and deep learning methods.
Ricco Zeegelaar, Xinqi Yan, Lucas F. Jansen Klomp, Stefano Schivo, Janine N. Post   +4 more
wiley   +1 more source

Energy-Sufficiency for a Just Transition: A Systematic Review

Energies, 2020
Efforts to achieve an energy transition often neglect to account for the levelling of benefits realizable with higher levels of energy use, despite knowledge of a saturation effect and recognition of increasing harms of use. This research examines energy
Matthew J. Burke
doaj   +1 more source

Reconstructing enzyme evolution by protein engineering

FEBS Letters, EarlyView.
Natural enzyme evolution can be retraced by protein engineering methods such as directed evolution, rational design, and ancestral sequence reconstruction. These approaches reveal how enzymes emerged from ligand‐binding scaffolds, developed varying substrate preferences, formed oligomeric complexes, adapted to environmental changes, and evolved novel ...
Lukas Drexler, Markus R. Busch, Reinhard Sterner   +2 more
wiley   +1 more source

An epithelial GPR35 isoform supports tumor‐associated transcriptional and metabolic phenotypes

FEBS Letters, EarlyView.
GPR35 generates two functionally distinct isoforms with previously unresolved roles. GPR35‐short mediates immune‐cell chemotaxis, while GPR35‐long is enriched in colorectal cancer epithelium, where it supports increased metabolism, proliferation, and tumor‐associated transcriptional programs.
Jørgen D. Rønneberg, Martine Hjeltnes, Josephine Krieger, Joshua E. Elias, Maria Stensland, Kristian Holm, Xiaojun Jiang, Chuki Khangsar, Tuula A. Nyman, Arthur Kaser, Johannes R. Hov, Tom H. Karlsen, Nicole C. Kaneider, Frode L. Jahnsen, Georg Schneditz   +14 more
wiley   +1 more source

Critical Minerals for a Just Energy Transition

Annual Review of Resource Economics
This article provides a critical review of the socioeconomic impacts of mining critical raw materials (CRMs), whose global demand is rising at an unprecedented pace due to the ongoing energy transition. Our review focuses on five key socioeconomic aspects: health, employment, human development, public services, and culture.
Comincioli, N., Knittel, C. R., Olivetti, E. A., Romani, I. G., Vergalli, S.   +4 more
openaire   +2 more sources

Stepping Into the Just Transition Journey: The Energy Transition in Petrostates

SSRN Electronic Journal
With the transition towards a low carbon economy underway, the notion of ensuring that it is a just transition – one that is fair and equitable – has captured significant attention in recent decades. Although petrostates are a central part of the fossil fuel-based global economy, they have been largely ignored in discussions of a just transition.
Hasan, Qaraman, Heffron, Raphael, Mohtadi, Soran, Blankenship, Brian, Overland, Indra, Urpelainen, Johannes   +5 more
openaire   +2 more sources