Results 111 to 120 of about 121,183,570 (291)
Unlocking the potential of cell‐permeable nanobodies for intracellular applications
FEBS Letters, EarlyView.This review outlines current strategies for delivery of nanobodies into cells and highlights recent examples of functional applications. By addressing and manipulating intracellular targets, these molecules hold great potential for treating cancer, respiratory diseases and neurological disorders, making this a vibrant area of research in the biomedical
Mariona Gené‐Verdés +2 more
wiley +1 more source
Just-in-time -JIT- in der Montage
, 2022 S.38-39Die aufbau- und ablauforganisatorische Schnittstelle zwischen Teilefertigung und Montage verhindert eine durchgängige Just-in-time-Produktion.
Bühring, J., Fuchs, R.-M.
core +1 more source
A systematic review of mobile-based microlearning in adult learner contexts
Educational Technology & SocietyThis systematic review examines the empirical literature published between 2015 and 2021 on mobile-based microlearning in adult learning contexts. The rapid shift to online learning in 2020 in response to the global COVID-19 pandemic has emphasized the ...
Robert L. Moore +2 more
doaj +1 more source
How structural disorder and polyelectrolyte properties of prothymosin α enable its large interactome
FEBS Letters, EarlyView.In this review, complexes of the fully disordered and highly negatively charged prothymosin α are collected, described, and discussed. Linked to its poly‐electrostatic character, prothymosin α engages a large interactome through multiple different binding modes ranging from fully disordered complexes to short linear motif (SLiM)‐driven interactions ...
Ketty C. Tamburrini +3 more
wiley +1 more source
Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment
Molecular Oncology, EarlyView.This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley +1 more source
Tec Empresarial, 2013 La tendencia mundial es la formación de bloquescomerciales crecientes mediante la expansión geográficade los mercados. Esto permite nuevas oportunidadesy, a su vez, crea nuevas amenazas debido a la “proliferación”de la competencia.
Ronald Leandro Elizondo
doaj
Molecular Oncology, EarlyView.This study shows that lung adenocarcinomas exploit developmental branching morphogenesis to acquire a therapy resistant basal‐like tumour cell state. This process was found to be regulated by combined TP53 loss‐of‐function and type‐I interferon signalling, identifying a novel axis for biomarker and therapeutic target discovery.
Kamila J Bienkowska +13 more
wiley +1 more source
Molecular Oncology, EarlyView.Circulating microRNAs as biomarkers of cachexia and sex‐specific cancer in senior dogs. In 25 client‐owned dogs, four circulating miRNAs (miR‐15a, miR‐15b, miR‐16, miR‐140) were downregulated in cachexia, with miR‐16 the strongest individual biomarker (AUC = 0.899).
Soon‐Seok Park +6 more
wiley +1 more source
Just-in-Time versus Just-in-Case: Inventory systems and their potential impact on Caribbean Companies [PDF]
The transition from Just-In-Time to Just-In-Case inventory systems has been discussed for over twenty years. The implications for such a change are possibly more problematic for Caribbean companies and economies than for others.
Sharland, Alex, MacLatchie, John
core +1 more source