Results 151 to 160 of about 9,491,894 (280)
Nuclear pore links Fob1‐dependent rDNA damage relocation to lifespan control
Damaged rDNA accumulates at a specific perinuclear interface that couples nucleolar escape with nuclear envelope association. Nuclear pores at this site help inhibit Fob1‐induced rDNA instability. This spatial organization of damage handling supports a functional link between nuclear architecture, rDNA stability, and replicative lifespan in yeast.
Yamato Okada +5 more
wiley +1 more source
Just-in-Time: Statewide Preceptor Development Through Brief Asynchronous Modules. [PDF]
Smith KL +6 more
europepmc +1 more source
Time‐resolved X‐ray solution scattering captures how proteins change shape in real time under near‐native conditions. This article presents a practical workflow for light‐triggered TR‐XSS experiments, from data collection to structural refinement. Using a calcium‐transporting membrane protein as an example, the approach can be broadly applied to study ...
Fatemeh Sabzian‐Molaei +3 more
wiley +1 more source
GamblingLess: In-The-Moment: a mixed-methods acceptability and engagement evaluation of a gambling just-in-time adaptive intervention. [PDF]
Dowling NA +7 more
europepmc +1 more source
Promiscuous stimulation of HSP70 ATPase activity by parasite‐derived J‐domains
The malaria parasite Plasmodium falciparum exports three highly homologous yet functionally divergent J‐domain proteins into human erythrocytes. Here, we show that J‐domains isolated from all three proteins effectively stimulate the ATPase activity of both endogenous host and exported parasite HSP70 chaperones.
Julian Barth +6 more
wiley +1 more source
Leveraging just-in-time simulation to train ad hoc teams. [PDF]
Tung MG +5 more
europepmc +1 more source
A Just-in-Time Video Primer on Pneumothorax Pathophysiology and Early Management [PDF]
Chi Zhang, Xiao +4 more
core
The Aging Blood: Cellular Origins, Circulating Drivers, and Therapeutic Potential
As a conduit linking all organs, the blood system both reflects and actively drives systemic aging. This review highlights how circulating pro‐aging and antiaging factors and age‐associated hematopoietic stem cell dysfunction contribute to immunosenescence and multi‐organ decline, positioning the hematopoietic system as a target for aging intervention.
Hanqing He, Jianwei Wang
wiley +1 more source
Just-in-time simulation for ad hoc teams: applications for surgical trainees. [PDF]
Shewmaker GS, Aladegbami B.
europepmc +1 more source

