Results 51 to 60 of about 2,030,000 (262)
Diversity and complexity in neural organoids
FEBS Letters, EarlyView.Neural organoid research aims to expand genetic diversity on one side and increase tissue complexity on the other. Chimeroids integrate multiple donor genomes within single organoids. Self‐organising multi‐identity organoids, exogenous cell seeding, or enforced assembly of region‐specific organoids contribute to tissue complexity.
Ilaria Chiaradia, Madeline A. Lancaster
wiley +1 more source
FEBS Letters, EarlyView.Embryo‐like structures (stembryos) are an innovative tool, but they are hindered by experimental variability and limited developmental potential. DNA methylation is crucial for mammalian development, but its status in stembryo models is poorly characterized.
Sara Canil +4 more
wiley +1 more source
Ingeniare: Revista Chilena de Ingeniería, 2008 This study presents a new mathematical model and a Greedy Randomized Adaptive Search Procedure (GRASP) meta-heuristic to solve the ordered cutting stock problem. The ordered cutting stock problem was recently introduced in literature.
Rodrigo Rabello Golfeto +2 more
doaj
Operator Idle Time Rectification as the Solution to Cycle Time Reduction in Oxygen Sensor Production
JIRAE (International Journal of Industrial Research and Applied Engineering), 2018 In factory works, there are systems that need to be followed in order to create a well-ordered process such that Just In Time (JIT) production can be reached. The lean manufacturing principle is one of the solutions for sustainable factory system. Within
Melvin Harsono, Joni Welman Simatupang
doaj +1 more source
FEBS Letters, EarlyView.Ascidian Ciona larvae initially show strong clockwise tail twisting, which is largely corrected during development. However, a small residual twist remains. This study shows that organized helical myofibrils in tail muscles mechanically stabilize this residual asymmetry, preventing complete restoration of bilateral symmetry and revealing how embryos ...
Yuki S. Kogure +3 more
wiley +1 more source
Assessing Patron Driven Acquisition (PDA) adoption among Malaysian academic libraries
Pakistan Journal of Information Management & Libraries, 2020 This study aims to explore the adoption of the Patron Driven Acquisition (PDA) model among Malaysian academic libraries. The study ensues the continuous increase in the proportion and cost of information resources (electronic and print) coupled with the ...
Aliyu Olugbenga Yusuf +1 more
doaj
Stochastic models of simple controlled systems just-in-time
Vestnik Samarskogo Gosudarstvennogo Tehničeskogo Universiteta. Seriâ: Fiziko-Matematičeskie Nauki, 2018 We propose a new and simple approach for the mathematical description of a stochastic system that implements the well-known just-in-time principle. This principle (abbreviated JIT ) is also known as a just-in-time manufacturing or Toyota Production ...
Alexander A Butov, Anatoly A Kovalenko
doaj +1 more source
FEBS Letters, EarlyView.Septin 9 polybasic domains couple phosphoinositide‐rich membrane binding to centrosome positioning, Golgi organization, and microtubule acetylation to control epithelial polarity. Their loss disrupts this axis, causing centrosome mispositioning, Golgi fragmentation, reduced microtubule acetylation, and polarity inversion via upregulation of the ...
Ting ting Cai +4 more
wiley +1 more source
Modulation of Homer1 EVH1 domain internal dynamics by putative autism‐associated mutations
FEBS Letters, EarlyView.The putative autism‐associated M65I and S97L variants of the EVH1 domain of the postsynaptic scaffold protein Homer1 do not exhibit substantial changes in their overall structure or partner binding. Both of them, but especially the M65I variant, show altered internal dynamics relative to the wild‐type domain on the μs‐ms timescale, indicated by the ...
Fanni Farkas +6 more
wiley +1 more source
FEBS Letters, EarlyView.We present robust protocols for the preparation of supported lipid bilayers (SLBs) incorporating either Salmonella smooth LPS or outer membrane vesicles (OMVs). We use a combination of quartz crystal microbalance with dissipation (QCM‐D) and fluorescence microscopy to both characterize the SLBs of various compositions and to probe their interactions ...
Hudson P. Pace +6 more
wiley +1 more source