Results 81 to 90 of about 121,183,570 (291)

The microbiome in human skin aging

FEBS Letters, EarlyView.
Age‐related skin changes encompass the well‐known visible phenotypic alterations, together with microbiome dysbiosis and a series of molecular aging hallmarks. These hallmarks characterize not only a fully stablished aged phenotype but also the skin aging process itself.
Manuel Huerta Arana, Cornelia Wiegand, Omid Omrani, Mario Fabri   +3 more
wiley   +1 more source

Clinical coaches and patient safety – Just in time: A descriptive exploratory study

, 2021
Patient safety in hospitals is a key priority. Clinical coaches who educate, support and coach staff to deliver safe, high quality care, are ideally placed to positively influence patient safety.
Naumann, A, Geisler, K, Faithfull-Byrne, A, Thompson, L, Gonzalez, J, Lin, F, Moss, C, Kathryn Geisler, Cheryle Moss, Judith Gonzalez, Lorraine Thompson, Amanda Naumann, Frances Lin, Annette Faithfull-Byrne   +13 more
core   +1 more source

Autophagy and mitophagy in pancreatic β‐cell homeostasis and their involvement in diabetes pathophysiology

FEBS Letters, EarlyView.
This review focuses on the role of autophagy and mitophagy in maintaining pancreatic β‐cell function and homeostasis. We discuss how genetic defects affecting these pathways contribute to the development of type 1, type 2, monogenic, and gestational diabetes. We further explore their potential as therapeutic targets. Created in BioRender.
Yunkyeong Lee, Mingming Tong, Anna L. Gloyn   +2 more
wiley   +1 more source

Testing the Just-in-Time Inventory Model Effect on Organizational Effectiveness for Egyptian Manufacturing Industries [PDF]

المجلة العربية للإدارة
Inventories are playing vital role in every business, so organization needs to have proper control and management of inventories as it may lead to increase in manufacturing cost.
Nevien Khourshed, Amr Abdelaziz
doaj   +1 more source

Ligand‐dependent transcriptional heterogeneity in cell cycle gene expression delays G1/S entry

FEBS Letters, EarlyView.
EGF and HRG induce distinct G1/S progression programs in ErbB2‐amplified BT474 breast cancer cells. Despite activating the potent ErbB2–ErbB3 heterodimer, HRG does not accelerate cell‐cycle entry. Instead, EGF promotes earlier restriction‐point passage via ERK–FOS signaling, whereas HRG activates the AKT–MYC axis, driving transcriptional heterogeneity ...
Ririn Rahmala Febri, Ayaka Nagasato‐Ichikawa, Keita Iida, Shuhei Kimura, Akira Imamoto, Mariko Okada   +5 more
wiley   +1 more source

Redefinition of De' Longhi logistic flows through Just-In-Time strategy

, 2022
reservedOggigiorno la pressione della concorrenza spinge le diverse realtà aziendali verso una continua ricerca del miglioramento (Kaizen). A questo proposito una delle strategie adottate consiste nell’implementazione delle pratiche di produzione snella
GUERRA, GRETA
core  

A Comparative Study of Commit Representations for JIT Vulnerability Prediction

Computers
With the evolution of software systems, their size and complexity are rising rapidly. Identifying vulnerabilities as early as possible is crucial for ensuring high software quality and security.
Tamás Aladics, Péter Hegedűs, Rudolf Ferenc   +2 more
doaj   +1 more source

Emerging experimental and computational methods for studying redox‐regulated structural transitions

FEBS Letters, EarlyView.
Redox reactions can reshape proteins and alter how they behave in cells, with important consequences for health and disease. This review explores emerging experimental and computational approaches for discovering these redox‐sensitive protein switches, revealing their structural effects, and predicting their behavior, opening new opportunities to ...
Tasneem Rass, Dana Reichmann, Gábor Erdős   +2 more
wiley   +1 more source

Translophagy—A potential link between autophagy impairment and translational errors

FEBS Letters, EarlyView.
Neurodegenerative diseases are characterised by the accumulation of abnormal proteins and protein aggregates, but their origin often remains unknown. We propose that selective autophagy removes damaged protein‐making machinery, preventing errors during protein synthesis.
Mykola V. Korolchuk, Gailing Ma, Robin Antrobus, Diego Manni, Marco Trevisan‐Herraz, Mustafa Khwaja, Max Brown, Gavin D. Richardson, Masaaki Komatsu, Daniel Erskine, Viktor I. Korolchuk, Tetsushi Kataura   +11 more
wiley   +1 more source

A Comparative study of DNA Alignment Algorithms and Boosting Performance Using Different Compilation Strategies

Cumhuriyet Science Journal
With the development of next generation sequencing technologies, the requirement of higher performance from DNA and Protein sequence alignment algorithms has become even greater.
Osman Doluca
doaj   +1 more source