Results 21 to 30 of about 391,277 (261)

Integrated use of meteorological and hydrological indices for drought early warning in the mountainous catchments of the Himalaya-Karakorum-Hindukush region

Scientific Reports
Effective drought monitoring, prediction and early warning systems are crucial for optimized management of human activities associated with water use in a climate affected world.
Taimoor Akhtar, Haris Mushtaq, Muhammad Zia-ur-Rahman Hashmi   +2 more
doaj   +1 more source

PLGA based formulations with poly(2-oxazoline)s for controlled dexamethasone release from thin extrudates

International Journal of Pharmaceutics: X
PLGA is a landmark in polymer-based drug delivery, due to its biocompatibility, biodegradability and great mechanical strength. However, its high mechanical resistance tends to be unfavorable for implantation, as it creates sharp edges upon rupture ...
Philipp S. Hilgeroth, Eric Lehner, Juliana Martins-Schalinski, Karsten Mäder, Wolfgang H. Binder   +4 more
doaj   +1 more source

Natural Killer Cells in Paediatric Soft Tissue Sarcomas: A Systematic Review

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Paediatric soft tissue sarcomas (pSTS) are a rare and heterogeneous group of malignant tumours arising in tissues of mesenchymal origin. The role of natural killer (NK) cells in pSTS remains poorly understood, with evidence fragmented across small preclinical studies and early‐phase clinical trials.
Raya Dean, Lara V. Graham, Christina Putnam, Rosa Gomes Alves Martins, Daniel T. Harding, Tim J. Underwood, Zoë S. Walters, Matthew D. Blunt   +7 more
wiley   +1 more source

Valorization of oil-extraction chia seed flour into injection-moulded biocomposites: Influence of plasticizers

Industrial Crops and Products
The valorization of agro-industrial by-products into scalable bioplastics is a key strategy for developing sustainable materials. In this work, chia seed flour (CSF), a by-product of cold oil extraction with medium protein (∼41 wt%) and high carbohydrate
I. Dominguez-Candela, I. Boronat-Castellar, M. Miranda-Pinzon, A. Martinez-Felipe, V. Fombuena   +4 more
doaj   +1 more source

Time to Diagnosis Among Children and Adolescents With Cancer in Québec, Canada: A Population‐Based Study

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Background Timely cancer diagnosis in children and adolescents is important to improving outcomes. We aimed to quantify time to diagnosis and assess variations by patient, demographic and system‐level factors. Procedure We conducted a population‐based study of individuals aged 0–19 years diagnosed with one of 12 cancers from 2010 to 2022 in ...
Callum Mullen, Ronald D. Barr, Erin Strumpf, Mariam El‐Zein, Eduardo L. Franco, Talía Malagón   +5 more
wiley   +1 more source

Identifying, improving, and investing in national commitments to just transition: Reflections from Latin America and the Caribbean

Environmental and Sustainability Indicators, 2023
A 1.5 °C world relies on the development of modern renewable energy sources in Latin America and the Caribbean. Whilst existing research offers insights into national case studies, our study responds to a lack of region-wide analysis.
Darren McCauley, Kerry A. Pettigrew, Raphael J. Heffron, Sufyan Droubi   +3 more
doaj   +1 more source

Impact of Japan's 2024 Physician Work‐Style Reform on Pediatric Hematology–Oncology: Educational Implications in a 2‐Year Survey

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Background Japan's 2024 physician work‐style reform introduced legally binding limits on physicians’ working hours, but its impact on education and workforce sustainability in pediatric hematology–oncology (PHO) remains unclear. Procedure We conducted a repeated cross‐sectional study with structured quantitative items and free‐text responses ...
Kiyohiko Kaizu, Masaharu Akiyama, Toshikazu Itabashi, Jun Hayakawa, Takahiro Kikuchi, Ryohei Fukunaga, Katsuyoshi Koh, Takahiro Ueda   +7 more
wiley   +1 more source

Opportunities and challenges of sequential extraction of silicon in contrasting soils

Frontiers in Environmental Science
IntroductionThe importance of silicon for soil functioning has only recently received the attention it deserves in soil science (and ecology). To identify the actual effects of Si on ecosystem functioning, a precise knowledge about different Si soil ...
Mathias Stein, Mathias Stein, Simone Kilian Salas, Reinhard Kleeberg, Hermann F. Jungkunst, Jörg Schaller   +5 more
doaj   +1 more source

European Environment, Social, and Governance Norms and Decent Work: Seeking a Consensus in the Literature

Social Sciences, 2023
Decent Work is considered essential to the facilitation of a transition to greener, fairer, more prosperous, and more just societies. Decent Work represents a fundamental component of the Sustainable Development Goals (SDGs) and a crucial facet of ...
Agnieszka Dziewulska, Colin W. P. Lewis
doaj   +1 more source

Protein pyrophosphorylation by inositol pyrophosphates — detection, function, and regulation

FEBS Letters, EarlyView.
Protein pyrophosphorylation is an unusual signaling mechanism that was discovered two decades ago. It can be driven by inositol pyrophosphate messengers and influences various cellular processes. Herein, we summarize the research progress and challenges of this field, covering pathways found to be regulated by this posttranslational modification as ...
Sarah Lampe, Tanmay Kumar Mohanty, Rashna Bhandari, Dorothea Fiedler   +3 more
wiley   +1 more source