Results 151 to 160 of about 2,085,954 (304)

Blood‐based proteomic profiling reveals context‐dependent changes in BCL2‐associated signaling during taxane therapy in breast cancer patients

FEBS Open Bio, EarlyView.
Chemotherapy side effects significantly impact cancer survivors' quality of life. Using protein levels in blood samples from breast cancer patients before and after 12 weeks of taxane treatment, we detected treatment‐dependent changes in calcium signaling and aging pathways associated with cancer recurrence.
Saira Munshani, Eiman Y. Ibrahim, Rozalyn L. Rodwin, Leah M. Ferrucci, Kim Blenman, Maryam Lustberg, Barbara E. Ehrlich   +6 more
wiley   +1 more source

Beyond the Battlefield: The Park That Once Was Stevens’s Furnace

, 2016
If you’re a frequent reader of the Compiler, it comes as no news to you that the Gettysburg area is historic for more than just its battlefield. From a pre-war African American community to the World War I tank camp commanded by a young Dwight Eisenhower,
Lavery, Kevin P.
core  

YIPFα1A expression is regulated by multilayered molecular mechanisms

FEBS Open Bio, EarlyView.
YIPFα1A, a five‐pass Golgi protein, is regulated at multiple layers. (1) Rare‐codon enrichment drives translation‐coupled mRNA decay. (2) A proximal 3′‐UTR element stabilizes mRNA. (3) A distal 3′‐UTR element included by alternate poly(A) site usage represses translation, which can be overridden by the proximal 3′‐UTR element.
Tokio Takaji, Yurika Nakanishi, Nobuhiro Nakamura   +2 more
wiley   +1 more source

Long-term psychological effects of war trauma and migration: an interpretative phenomenological analysis of Balkan war survivors. [PDF]

BMC Psychol
Nečasová M, Preiss M, Ulčák D, Rektor I, Prokopová A, Fňašková M.   +5 more
europepmc   +1 more source

Rebel Recruitment in a Coffee Exporting Economy [PDF]

Recent literature in the political economy of civil war has pointed to the importance of (changes) in the economic environment for the understanding of conflict dynamics.
Eleonora Nillesen, Philip Verwimp
core  

Identifying transcription factors controlling the basal expression of human MRP4 highlights a substantial role for Sp1

FEBS Open Bio, EarlyView.
The MRP4 transporter exports several drugs and signaling molecules. Here, we identified key promoter elements regulating basal MRP4 expression. Using reporter assays, we defined a conserved region with essential Sp1 and contributory Ets sites, which controlled basal MRP4 expression.
Debora Singer, Angelique Kragl, Katrin Ziems, Juliane Glaubitz, Sophie Grammbauer, Susanne Hildebrandt, Mladen V. Tzvetkov, Gabriele Jedlitschky   +7 more
wiley   +1 more source

Just war [PDF]

, 2018
openaire   +2 more sources

The Life and Legacy of Dr. Jonathan Letterman (1824-1872): The Father of Modern Battlefield Medicine. [PDF]

Cureus
Carter J, Meyers N.
europepmc   +1 more source

2 Comments on Gettysburg’s Stone Walls: Restoration or Rehabilitation? “Wirz’s Jewelry”: Memories of Captivity

, 2018
This post is part of a series featuring behind-the-scenes dispatches from our Pohanka Interns on the front lines of history this summer as interpreters, archivists, and preservationists. See here for the introduction to the series.
Greenman, Jessica Nicole
core  

Derivation and characterization of retinal pigment epithelium from urine‐derived iPSCs

FEBS Open Bio, EarlyView.
Age‐related macular degeneration causes vision loss via RPE dysfunction and loss. Traditional iPSC therapies rely on invasive biopsies, limiting scalability. Here, we utilize urine‐derived stem cells as an accessible source to generate u‐iPSCs, successfully differentiated into pigmented RPE. This “Urine‐to‐Retina” platform provides a promising path for
Daniella Beiner, Hainan Zhu, Carol Christine Bosholm, Heuy‐Ching Wang, Tracy Criswell, Anthony Atala, Jian‐Xing Ma, Yuanyuan Zhang   +7 more
wiley   +1 more source