Results 201 to 210 of about 6,397,857 (332)

Medicating to practice: a mixed-methods study of Ukrainian psychotherapists in a shared trauma context. [PDF]

Front Psychol
Martyniuk O.
europepmc   +1 more source

TRPML1 agonist ML‐SA5 attenuates pulmonary fibroblast activation by suppressing mTOR and restoring autophagic flux

FEBS Open Bio, EarlyView.
TGF‐β1 stimulation downregulates lysosomal channel TRPML1 in pulmonary fibroblasts. The TRPML1 agonist ML‐SA5 suppressed fibroblast‐to‐myofibroblast activation and collagen production. Mechanistically, ML‐SA5 inhibited mTOR phosphorylation, restored autophagic flux, and its effects were enhanced by rapamycin (mTOR inhibitor) and reversed by MHY1485 ...
Jiatong Yao, Xiaoting Kang, Lulu Meng, Shaoxuan Zhang, Qiujie Li, Jinyu Zhou, Mengyue Xue, Chu Li, Hua Zhu, Pengzhou Hang, Jing Zhao   +10 more
wiley   +1 more source

Resilience amid conflict: a qualitative study of perspectives on the provision of and experience with sexual and reproductive health services during war. [PDF]

BMC Health Serv Res
Kabakian-Khasholian T, Abi Jaoude L, El Chaar D, Saad GE, El Fakahany S, McCall SJ, El-Kak F.   +6 more
europepmc   +1 more source

Chronobiology of Cancer: How Aging Fuels Oncogenesis at the Molecular Level

Aging and Cancer, EarlyView.
This graphical abstract illustrates the key biological pathways linking aging with cancer development and progression. In the upper left, cumulative exposure to ultraviolet radiation, toxins, and reactive oxygen species (ROS) causes DNA damage and genomic instability, whereas age‐related decline in repair mechanisms, such as ATM/ATR, BER, and NER ...
Anu Singh, Aroonima Misra, Sufian Zaheer
wiley   +1 more source

A novel approach to blood supply in the era of large-scale combat operations. [PDF]

J Trauma Acute Care Surg
Hazen BJ, Staak BP, Holcomb JB, Birmingham, Alabama.   +4 more
europepmc   +1 more source

A Low Psoas Muscle Index Was Associated With a Poorer Overall Survival in Patients Who Underwent Percutaneous Nephrostomy

Aging and Cancer, EarlyView.
In patients with malignant ureteral obstruction undergoing percutaneous nephrostomy, sarcopenia defined by a low psoas muscle index was independently associated with poor overall survival on multivariate Cox regression analysis, suggesting that preoperative assessment of psoas muscle index may aid prognostic stratification in this population.
Kota Shimokihara, Takashi Kawahara, Kazuhide Makiyama, Hiroji Uemura   +3 more
wiley   +1 more source

'Opening' the closed method: military-civilian exchanges and transatlantic circulations in Manuel Bastos' early work on compound fractures (1909-24). [PDF]

Med Hist
Martinez FJ, Murillo-Arribas C.
europepmc   +1 more source

Self‐Regulated Learning Meets AI: Reinterpreting Self‐Regulation, Co‐Regulation, and Socially Shared Regulation in Human–AI Interaction

New Directions for Adult and Continuing Education, EarlyView.
ABSTRACT Advancing artificial intelligence (AI) has transformed learning and work, yet higher education and professional development programs have not systematically equipped learners for AI‐prevalent environments. This lack of preparation creates uncertainty regarding control, responsibility, trust, and accountability.
Moon‐Heum Cho, Jerusalem Merkebu
wiley   +1 more source

Invisible wounds, visible crisis: rethinking chronic pain, PTSD, and traumatic brain injury in veterans worldwide. [PDF]

Korean J Pain
Lacsa JEM.
europepmc   +1 more source

Not Just War, But A Just War : Individual rights versus the collective good in just cause for war

, 2021
openaire   +1 more source