Results 31 to 40 of about 103,560 (303)

Structural instability impairs function of the UDP‐xylose synthase 1 Ile181Asn variant associated with short‐stature genetic syndrome in humans

open access: yesFEBS Letters, EarlyView.
The Ile181Asn variant of human UDP‐xylose synthase (hUXS1), associated with a short‐stature genetic syndrome, has previously been reported as inactive. Our findings demonstrate that Ile181Asn‐hUXS1 retains catalytic activity similar to the wild‐type but exhibits reduced stability, a looser oligomeric state, and an increased tendency to precipitate ...
Tuo Li   +2 more
wiley   +1 more source

Supreme Threat: The Just War Tradition and the Invasion of Iraq

open access: yes, 2006
This work intends to be an application and understanding of the Christian just war tradition as it pertains to the actions of the United States government in Iraq.
Fallaize, James
core   +1 more source

Jus post bellum and Global Responsibility for Peace

open access: yesProfil, 2020
The article deals with the newly discussed set of principles that focus on various issues concerning the end of a war and the establishment of peaceful conditions for the society after a war ends.
Lukáš Švaňa
doaj   +1 more source

Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system

open access: yesFEBS Letters, EarlyView.
Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley   +1 more source

The concept of rights in the justification of the “just war”

open access: yesFilosofia Unisinos, 2012
The theory of “just war” of Walzer, is a theory about the justification of states to go to war, as presented in his book: Just and unjust wars, whose central thesis is based on the following proposition: the only justification for going to war is the ...
Raúl Andrés Jaramillo Echavarría
doaj   +1 more source

Diversity and complexity in neural organoids

open access: yesFEBS Letters, EarlyView.
Neural organoid research aims to expand genetic diversity on one side and increase tissue complexity on the other. Chimeroids integrate multiple donor genomes within single organoids. Self‐organising multi‐identity organoids, exogenous cell seeding, or enforced assembly of region‐specific organoids contribute to tissue complexity.
Ilaria Chiaradia, Madeline A. Lancaster
wiley   +1 more source

Pacifist rejoinders to the ‘Hitler question’

open access: yesEuropean Journal of International Security
This article tackles head-on a question that is often thought to defeat pacifism: ‘How then would you react against a Nazi invasion?’ That multiple wars are still recurrently justified as necessary to confront yet another ‘Hitler’ makes tackling this ...
Alexandre Christoyannopoulos
doaj   +1 more source

Wojna sprawiedliwa versus wojna święta

open access: yesPoliteja, 2013
Just war versus holy war. The doctrinal issues of the historical confrontation In the first part of their article, the Authors outline the relations between the meaning of realism, pacifism, and the notion of just war.
Zbigniew Rau, Tomasz Tulejski
doaj   +1 more source

Epigenetic blind spots – the role of DNA methylation dynamics in stem cell‐based models of embryogenesis

open access: yesFEBS Letters, EarlyView.
Embryo‐like structures (stembryos) are an innovative tool, but they are hindered by experimental variability and limited developmental potential. DNA methylation is crucial for mammalian development, but its status in stembryo models is poorly characterized.
Sara Canil   +4 more
wiley   +1 more source

Rewriting the just war tradition: just war in classical Greek political thought and practice [PDF]

open access: yes, 2015
The just war tradition is the predominant western framework for thinking about the ethics of contemporary war. Political and military leaders frequently invoke its venerable lineage to lend ballast to their arguments for or against particular wars.
O'Driscoll, Cian, Cian O'Driscoll
core   +1 more source

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