Results 101 to 110 of about 1,123,097 (347)

Tissue‐Resident Macrophage‐Derived E3 Ligase SMURF2 Restricts Autoimmune Inflammation by Mediating the Degradation of p‐TBK1

open access: yesAdvanced Science, EarlyView.
Dysregulated Tissue resident macrophage (TRMs) link to autoimmune inflammation. SMURF2 mediates Lys‐27 (K27)‐linked ubiquitination of p‐TBK1 and its degradation, which inhibits CSF1R signaling‐triggered TRM proliferation, thereby restraining the autoimmune inflammation.
Xiang An   +8 more
wiley   +1 more source

Book Review

open access: yes, 2003
This concise book explores the origins and early history of the Cook County Juvenile Court, the world’s first such court. The court, which opened on July 3, 1899, in Chicago, reflected its founders’ profound faith both in science to solve social problems
Tanenhaus, David S.
core  

Assessing Juvenile Psychopathy: Developmental and Legal Implications [PDF]

open access: yes, 2006
Psychopath. The word alone evokes powerful emotions and images. Attaching that label to a juvenile offender is a serious charge, and should be done so with caution, especially given that the standard assessment tools for psychopathy were originally ...

core  

Plant Virus‐Induced Inheritable Apoptosis Drives Reproductive Costs in Female Insect Vectors to Balance Viral Biparental Transmission

open access: yesAdvanced Science, EarlyView.
Rice gall dwarf virus (RGDV), transmitted biparentally by leafhopper vector to their offspring, exploits the capsid protein to induce inheritable ovarian apoptosis via insulin‐driven PI3K/AKT/FoxO signaling axis. This mechanism enhances infection but reduces female reproductive fitness, causing inefficient maternal transmission.
Haibo Wu   +6 more
wiley   +1 more source

Development and validation of China’s Environmental Citizenship Questionnaire: evidence from junior high school students

open access: yesFrontiers in Environmental Science
The cultivation of environmental citizens has become an important measure to cope with the environmental crisis, and the research on the knowledge, conceptions, skills, attitudes, values, and actions of environmental citizens using the Environmental ...
Junhong Gao, Yong Jiang
doaj   +1 more source

What’s Wrong With Victims’ Rights in Juvenile Court?: Retributive v. Rehabilitative Systems of Justice [PDF]

open access: yes, 2009
While scholars have written extensively about the victims’ rights movement in capital and criminal cases, there has been very little discussion about the intersection of victims’ rights and the juvenile justice system.
Henning, Kristin N.
core   +1 more source

HMGB2 Promotes Cardiomyocyte Proliferation and Heart Regeneration Through MTA2‐Driven Metabolic Reprogramming

open access: yesAdvanced Science, EarlyView.
In contrast to the adult mammalian heart, which lacks regenerative capacity, the neonatal heart retains a transient regenerative capacity. In this study, high mobility group box 2 (HMGB2) is identified as a crucial protein driving heart regeneration based on comprehensive analyses using quantitative proteomics with tandem mass tag (TMT) labelling, RNA ...
Liu‐Hua Zhou   +17 more
wiley   +1 more source

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