Results 1 to 10 of about 753,139 (314)

LACC1 deficiency links juvenile arthritis with autophagy and metabolism in macrophages. [PDF]

J Exp Med, 2021
Juvenile arthritis represents the most common rheumatic manifestation in children. LACC1 deficiency has been identified as a monogenic cause of juvenile arthritis. In this issue, Omarjee et al.
Omarjee O, Mathieu AL, Quiniou G, Moreews M, Ainouze M, Frachette C, Melki I, Dumaine C, Gerfaud-Valentin M, Duquesne A, Kallinich T, Tahir Turanli E, Malcus C, Viel S, Pescarmona R, Georgin-Lavialle S, Jamilloux Y, Larbre JP, Sarrabay G, Magnotti F, Rice GI, Bleicher F, Reboulet J, Merabet S, Henry T, Crow YJ, Faure M, Walzer T, Belot A.   +28 more
europepmc   +2 more sources

Definition and Validation of the American College of Rheumatology 2021 Juvenile Arthritis Disease Activity Score Cutoffs for Disease Activity States in Juvenile Idiopathic Arthritis. [PDF]

Arthritis Rheumatol, 2021
To develop and validate new Juvenile Arthritis Disease Activity Score 10 (JADAS10) and clinical JADAS10 (cJADAS10) cutoffs to separate the states of inactive disease (ID), minimal disease activity (MiDA), moderate disease activity (MoDA), and high ...
Trincianti C, Van Dijkhuizen EHP, Alongi A, Mazzoni M, Swart JF, Nikishina I, Lahdenne P, Rutkowska-Sak L, Avcin T, Quartier P, Panaviene V, Uziel Y, Pruunsild C, Vargova V, Vilaiyuk S, Dolezalova P, Ringold S, Garrone M, Ruperto N, Ravelli A, Consolaro A, Paediatric Rheumatology International Trials Organisation.   +21 more
europepmc   +2 more sources

Juvenile idiopathic arthritis

Nature Reviews Disease Primers, 2022
Juvenile idiopathic arthritis (JIA) is an umbrella term for arthritis of unknown origin, lasting for >6 weeks with onset before 16 years of age. JIA is the most common chronic inflammatory rheumatic condition of childhood. According to the International League Against Rheumatism (ILAR) classification, seven mutually exclusive categories of JIA exist ...
A. Martini, D. Lovell, S. Albani, H. Brunner, K. Hyrich, S. Thompson, N. Ruperto   +6 more
semanticscholar   +3 more sources

Emergent high fatality lung disease in systemic juvenile arthritis. [PDF]

Ann Rheum Dis, 2019
Objective To investigate the characteristics and risk factors of a novel parenchymal lung disease (LD), increasingly detected in systemic juvenile idiopathic arthritis (sJIA). Methods In a multicentre retrospective study, 61 cases were investigated using
Saper VE, Chen G, Deutsch GH, Guillerman RP, Birgmeier J, Jagadeesh K, Canna S, Schulert G, Deterding R, Xu J, Leung AN, Bouzoubaa L, Abulaban K, Baszis K, Behrens EM, Birmingham J, Casey A, Cidon M, Cron RQ, De A, De Benedetti F, Ferguson I, Fishman MP, Goodman SI, Graham TB, Grom AA, Haines K, Hazen M, Henderson LA, Ho A, Ibarra M, Inman CJ, Jerath R, Khawaja K, Kingsbury DJ, Klein-Gitelman M, Lai K, Lapidus S, Lin C, Lin J, Liptzin DR, Milojevic D, Mombourquette J, Onel K, Ozen S, Perez M, Phillippi K, Prahalad S, Radhakrishna S, Reinhardt A, Riskalla M, Rosenwasser N, Roth J, Schneider R, Schonenberg-Meinema D, Shenoi S, Smith JA, Sönmez HE, Stoll ML, Towe C, Vargas SO, Vehe RK, Young LR, Yang J, Desai T, Balise R, Lu Y, Tian L, Bejerano G, Davis MM, Khatri P, Mellins ED, Childhood Arthritis and Rheumatology Research Alliance Registry Investigators.   +72 more
europepmc   +2 more sources

Clinical characteristics and genotype analysis of a Chinese patient with juvenile arthritis due to novel LACC1 frameshift mutation and literature review [PDF]

Molecular Genetics & Genomic Medicine, 2023
Background Some juvenile idiopathic arthritis (JIA) patients have a familial aggregation of the disease, and a few have been found to have a juvenile arthritis (JA) phenotype caused by a genetic mutation.
Yali Wu, Shasha Wang, Wen Yin, Wei Yin, Yan Ding   +4 more
doaj   +2 more sources

Temporomandibular joint disorders as the only manifestation of juvenile idiopathic arthritis: a case report [PDF]

Einstein (São Paulo), 2018
Juvenile idiopathic arthritis is a term used to include all chronic childhood arthritis of unknown etiology. It is characterized by chronic inflammation persisting for at least 6 weeks, beginning before 16 years of age.
José Renato Ribeiro Pinto, Irineu Gregnanin Pedron, Estevam Rubens Utumi, Milton Edson Miranda, Elisa Cruz Pereira Pinto, Leopoldo Penteado Nucci   +5 more
doaj   +2 more sources

Juvenile Idiopathic Arthritis

Balkan Medical Journal, 2017
Juvenile idiopathic arthritis is the most common chronic rheumatic disease of unknown aetiology in childhood and predominantly presents with peripheral arthritis.
Kenan Barut, Amra Adrovic, Sezgin Şahin, Özgür Kasapçopur   +3 more
doaj   +6 more sources

Young People’s, Parents’, and Professionals’ Views on Required Components of Mobile Apps to Support Self-Management of Juvenile Arthritis: Qualitative Study

JMIR mHealth and uHealth, 2018
BackgroundThere is growing evidence that supporting self-management of Juvenile Arthritis can benefit both patients and professionals. Young people with Juvenile Arthritis and their healthy peers increasingly use mobile technologies to access information
Waite-Jones, Jennifer M, Majeed-Ariss, Rabiya, Smith, Joanna, Stones, Simon R, Van Rooyen, Vanessa, Swallow, Veronica   +5 more
doaj   +2 more sources

‘The current mental health status of children and young people with JIA, and their wider family’: a charity partner collaboration survey

Pediatric Rheumatology Online Journal, 2023
Background This paper presents insight into the scale of mental health concerns for families who have a child or young person with a diagnosis of Juvenile Idiopathic Arthritis (JIA) living in any of the four nations of the United Kingdom (UK).
Polly Livermore, S. Ainsworth, R. Beesley, S. Douglas, E. Earle, D. Wilson, L. Woolley, J. Clinch   +7 more
doaj   +1 more source

Golimumab for Polyarticular Juvenile Idiopathic Arthritis and Psoriatic Arthritis: Pharmacologic and Clinical Considerations

Life, 2023
Psoriatic arthritis is a chronic debilitating autoimmune condition, and when diagnosed in patients before the age of eighteen, it is considered pediatric polyarticular juvenile idiopathic arthritis.
Sydney Moore McIntosh, Christian Kerut, Payton P. Hollenshead, Dorothy H. Askins, Kasra Mansourian, Zachary R. Palowsky, Varsha Allampalli, Shahab Ahmadzadeh, Sahar Shekoohi, Alan D. Kaye   +9 more
doaj   +1 more source