Results 91 to 100 of about 30,492 (254)

Juvenile chronic arthritis and imaging: comparison of different techniques

Reumatismo, 2001
Objective: The aim of this study was to compare imaging findings obtained with different techniques in a patient with juvenile chronic arthritis.
E. Filippucci, A. Farina, C. Cervini, W. Grassi   +3 more
doaj   +1 more source

Novel approaches for drug development against chronic primary pain: A systematic review

British Journal of Pharmacology, EarlyView.
Abstract Chronic primary pain (CPP) persisting for more than 3 months, associated with significant emotional distress without any known underlying cause, is an unmet medical need. Traditional or adjuvant analgesics do not provide satisfactory pain relief for a great proportion of these patients.
Valéria Tékus, Éva Borbély, Andreas Goebel, Ralf Baron, Zsófia Hajna, Zsuzsanna Helyes   +5 more
wiley   +1 more source

[Juvenile chronic arthritis: therapeutic strategy 1990]

, 1991
Therapeutic strategies based on experience with 119 patients with juvenile chronic arthritis are reviewed. Therapeutic goals are formulated and the means of attaining them (NSAIDs, the so-called disease modifying drugs gold, chloroquine and penicillamine,
Sauvain, M J, Gerber, N J
core  

Does age moderate self-pain enmeshment in chronic pain patients? [PDF]

, 2013
Research has demonstrated that chronic pain can compromise identity by becoming enmeshed and centralised with pain. Pain-identity enmeshment and pain-identity centrality are associated with greater affective distress and poorer chronic pain adjustment ...
Perry, Mark Paul
core  

Haemostatic changes and bleeding with anti‐IL‐6 directed therapy in autoimmune diseases

British Journal of Pharmacology, EarlyView.
Abstract Anti‐IL‐6 directed therapy, especially tocilizumab (TCZ), is widely used for the treatment of autoimmune diseases such as rheumatoid arthritis, giant cell arteritis and systemic juvenile idiopathic arthritis. Next to being a master regulator of inflammation, IL‐6 also is an important regulator of haemostasis. Although generally well tolerated,
Charlotte D. C. C. van der Heijden, Loes C. Oskam, Lenny van Bon, Chantal P. Rovers   +3 more
wiley   +1 more source

Systemic Juvenile Idiopathic Arthritis Complicated by Mesengioproliferative Glomerulonephritis

Turkish Journal of Nephrology, 2019
Juvenile idiopathic arthritis (JIA), one of the most common rheumatic diseases of childhood, is characterized by chronic synovitis and other organ dysfunctions.
İsmail DURSUN, Zübeyde GÜNDÜZ, Metin KAYA GÜRGÖZE, Hakan POYRAZOĞLU, Ruhan DÜŞÜNSEL, Arzu TAŞDEMİR   +5 more
doaj  

Role of interleukin-17 in juvenile idiopathic arthritis

Zdorovʹe Rebenka
Joint diseases is a pressing problem of pediatrics. Juvenile idiopathic arthritis is a common chronic systemic inflammatory disease of the joints in children; its etiological factors remain completely unknown.
I.A. Karimdzhanov, M.Sh. Madaminova
doaj   +1 more source

RHUPUS Syndrome in Children: A Case Series and Literature Review

Case Reports in Rheumatology, 2013
Objective. Overlap of juvenile idiopathic arthritis (JIA) and juvenile systemic lupus erythematosus (JSLE) is a rare clinical condition in children. This condition has been described as RHUPUS syndrome.
Vahid Ziaee, Mohammad Hassan Moradinejad, Reyhaneh Bayat   +2 more
doaj   +1 more source

Clinical and MRI outcome of cervical spine lesions in children with juvenile idiopathic arthritis treated with anti-TNFα drugs early in disease course

Pediatric Rheumatology Online Journal, 2017
Backgrounds The purpose of the study was to evaluate the clinical and magnetic resonance imaging (MRI) outcome of cervical spine arthritis in children with juvenile idiopathic arthritis (JIA), who received anti-TNFα early in the course of cervical spine ...
Damjana Ključevšek, Nina Emeršič, Nataša Toplak, Tadej Avčin   +3 more
doaj   +1 more source

A Phase 2 Trial of Frexalimab, a CD40L Antagonist, in Adolescents and Adults With Recent‐Onset Type 1 Diabetes (FABULINUS): Rationale and Study Design

Diabetes, Obesity and Metabolism, EarlyView.
ABSTRACT Introduction Type 1 diabetes (T1D) is a chronic autoimmune disease, characterised by progressive destruction of the insulin‐producing pancreatic β‐cells. Preserving remaining β‐cells at the time of diagnosis may improve long‐term outcomes. Frexalimab is a humanised monoclonal antibody specific for CD40L undergoing evaluation for treatment of ...
Andriy Cherkas, Baerbel Rotthaeuser, Niels Porksen, Pascale Labard, My‐Liên Nguyên‐Pascal, Mathieu Coudert, Baptiste Berthou, Marie Baccara‐Dinet, Gabor Boka, Mark Peakman, Felix Reschke, Michael J. Haller   +11 more
wiley   +1 more source