Results 131 to 140 of about 30,492 (254)

THERAPY OF R EFRACTOR Y JUVENILE CHRONIC ARTHRITIS

, 2001
Summary Up-to-date aspects of treatment of refractory form of juvenile chronic arthritis (JCA) is presented. JCA therapy by high doses of parenteral Methotrexate, tactics of combined using of disease modifying drugs, efficacy of «new» cytotoxic drugs ...
H Michels
core   +1 more source

Interleukin‐18 Levels Are Associated With Disease Course in Patients With Still Disease Treated With Interleukin‐1 Inhibitors

Arthritis &Rheumatology, Volume 78, Issue 6, Page 1327-1338, June 2026.
Objective To evaluate the prognostic utility of circulating interleukin‐18 (IL‐18) levels in predicting disease activity, macrophage activation syndrome (MAS), and disease course in patients with Still disease (SD) receiving first‐line IL‐1 inhibitors (IL‐1i).
Matteo Trevisan, Manuela Pardeo, Ivan Caiello, Claudia Bracaglia, Arianna De Matteis, Valentina Matteo, Elena Loricchio, Fabrizio De Benedetti, Giusi Prencipe   +8 more
wiley   +1 more source

Tacrolimus as Single‐Agent Immunotherapy for Adult‐Onset Myasthenia Gravis: Remission, Relapse, and Safety

CNS Neuroscience &Therapeutics, Volume 32, Issue 6, June 2026.
Tacrolimus monotherapy yields high remission in adult‐onset MG, especially in new‐onset or younger patients. Relapse is linked to low tacrolimus concentration and rapid tapering. Hyperglycemia was the most common ADR. Long‐term use may increase cancer risk.
Zhangyan Geng, Yuting Jiang, Nairong Xie, Wenjia Zhu, Hai Chen, Yaye Wang, Haoran Liu, Qinyao Liu, Congwen Lv, Yu Qian, Yan Lu, Li Di, Min Wang, Min Xu, Xinmei Wen, Bingchuan Xie, Yuwei Da   +16 more
wiley   +1 more source

Middle ear function in patients with juvenile chronic arthritis

, 1990
The conductive hearing of 18 patients with juvenile chronic arthritis was studied. Tympanometry was therefore undertaken for the assessment of functional state of the tympanic membrane, the ossicular chain with its ligaments and muscles, and the air ...
Siamopoulou-Mavridou, A., Skevas, A., Asimakopoulos, D., Mavridis, A., Moutsopoulos, H. M.   +4 more
core  

A novel LACC1 variant c.658G>A (p. Asp220Asn) in familial juvenile arthritis: identification and functional analysis

Human Genomics
Background Juvenile Idiopathic Arthritis (JIA) represents the most prevalent chronic rheumatic disease in childhood. Its etiology is multifactorial, with growing evidence pointing to a significant genetic contribution to disease susceptibility.
Hiba Alblooshi, Noor Mustafa, Azeem Abdul Khalam, Anjali Bharathan, Ekhlass Mohammed, Ibrahim Baydoun, Mohammed Tabouni, Mushal Allam, Meera Almansoori, Tabeer Fatima, Najla Aljaberi   +10 more
doaj   +1 more source

Relaxation Time Mapping of Early‐Stage Osteonecrosis of the Femoral Head: An In Vivo Piglet Model Study

Journal of Orthopaedic Research, Volume 44, Issue 6, June 2026.
T2, T1ρ, adiabatic T1ρ, and adiabatic T2ρ relaxation time mapping techniques are sensitive in detecting ischemic injury to bone marrow of the femoral head in vivo in a piglet model at 3 T MRI. T2 and adiabatic T2ρ relaxation times have the most pronounced increase in ischemic versus perfused, contralateral‐control femoral heads 1 week after induction ...
Casey P. Johnson, Erick O. Buko, Sampada Bhave, Kayla L. Chase, Douglas Albrecht, Alexandra R. Armstrong, Jutta M. Ellermann, Harry K. W. Kim, Ferenc Tóth   +8 more
wiley   +1 more source

Approach to Nail Pitting in Pediatric and Adolescent Patients: A Dermatology Perspective

JEADV Clinical Practice, Volume 5, Issue 2, Page 394-401, June 2026.
ABSTRACT This narrative review aims to discuss the etiologies of nail pitting in pediatric and adolescent patients, while providing a framework for further evaluation of possible underlying systemic conditions and their clinical findings from a dermatologic standpoint.
Elizabeth Botto, Victoria Griffith, Samuel Stahly, Jere Mammino   +3 more
wiley   +1 more source

Age‐Dependent Differences in Canakinumab Safety: A Comprehensive Pharmacovigilance Analysis Using the FAERS Database

Pharmacology Research &Perspectives, Volume 14, Issue 3, June 2026.
ABSTRACT While the efficacy of canakinumab, an anti‐interleukin‐1β monoclonal antibody, is well‐established, its safety profile, particularly across different age groups, remains inadequately explored. Using the FDA Adverse Event Reporting System (FAERS) database, this study evaluated postmarketing safety by analyzing adverse event (AE) reports from ...
Youyang Wang, Ngasin Lam, Xiaoming Huang, Yang Jiao   +3 more
wiley   +1 more source

Tubulointerstitial nephritis and uveitis syndrome in children: What to keep an eye on

Acta Ophthalmologica, Volume 104, Issue 4, Page e443-e452, June 2026.
Abstract Purpose The purpose of this study was to determine the disease course in patients with tubulointerstitial nephritis and uveitis (TINU) syndrome, focusing on long‐term outcome and the incidence of complications such as chronic kidney disease (CKD).
Jytte Hendrikse, Anne Sina Paula Simon, Viera Kalinina Ayuso, Joke Helena de Boer, Gerrit van den Berg   +4 more
wiley   +1 more source

Predictive Factors for Relapse in Still's Disease: A Retrospective Cohort Study of Clinical and Laboratory Biomarkers

Clinical and Translational Science, Volume 19, Issue 6, June 2026.
ABSTRACT This retrospective cohort study aimed to identify clinical and laboratory predictors of relapse in patients with Still's disease. A total of 94 patients diagnosed by Yamaguchi or Fautrel criteria across two rheumatology centers between 2012 and 2024 were evaluated, of whom 87 were eligible for analysis.
İbrahim Yahya Çakır, Abdulsamet Erden, Yeter Mahmutoğlu, Rıza Can Kardaş, Emine Uslu, Ertuğrul Çağrı Bölek, Serdar Sezer, Müçteba Enes Yayla, Hamit Küçük, Abdurrahman Tufan, Aşkın Ateş, Murat Turgay, Mehmet Akif Öztürk   +12 more
wiley   +1 more source