Results 251 to 260 of about 341,590 (292)
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Shared and Distinctive Transcriptomic and Proteomic Pathways in Adult and Juvenile Dermatomyositis
Arthritis & Rheumatology, 2023Transcript and protein expression were interrogated to examine gene locus and pathway regulation in the peripheral blood of active adult dermatomyositis (DM) and juvenile DM patients receiving immunosuppressive therapies.
James M. Ward +12 more
semanticscholar +1 more source
Arthritis & Rheumatology, 2023
This study was undertaken to identify blood markers of juvenile dermatomyositis (DM) disease activity (DA), which are needed to improve disease management.
Jacqueline S Gofshteyn +24 more
semanticscholar +1 more source
This study was undertaken to identify blood markers of juvenile dermatomyositis (DM) disease activity (DA), which are needed to improve disease management.
Jacqueline S Gofshteyn +24 more
semanticscholar +1 more source
Rheumatology, 2022
OBJECTIVE To evaluate the use of Janus kinase inhibitor (JAKi) in treating JDM and develop cytokine biomarkers of active disease. METHODS This study involved a retrospective cohort study that evaluated JAKi in 101 JDM patients as well as a cross ...
Baozhen Huang +11 more
semanticscholar +1 more source
OBJECTIVE To evaluate the use of Janus kinase inhibitor (JAKi) in treating JDM and develop cytokine biomarkers of active disease. METHODS This study involved a retrospective cohort study that evaluated JAKi in 101 JDM patients as well as a cross ...
Baozhen Huang +11 more
semanticscholar +1 more source
The Indian Journal of Pediatrics, 1996
The clinical profile of 7 children and their follow-up is described. There was female preponderance with mate to female ratio of 1:6. The median age of onset was 6 years. All the patients had skin rash, muscle weakness and abnormal enzyme profile. Muscle biopsy was performed in 6 and was abnormal in all of them.
O. P. Semwal +3 more
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The clinical profile of 7 children and their follow-up is described. There was female preponderance with mate to female ratio of 1:6. The median age of onset was 6 years. All the patients had skin rash, muscle weakness and abnormal enzyme profile. Muscle biopsy was performed in 6 and was abnormal in all of them.
O. P. Semwal +3 more
openaire +5 more sources
Zeitschrift für Rheumatologie, 2006
Juvenile dermatomyositis (JDM) is an inflammatory multi-system disease of unknown etiology with classic involvement of the skin and striated muscles. Following a prodromal period, patients develop a progressive proximal muscle weakness. Typical skin involvement includes heliotrope rash, facial erythema, Gottron's sign and nailfold capillary ...
H.-I. Huppertz, F. Dressler
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Juvenile dermatomyositis (JDM) is an inflammatory multi-system disease of unknown etiology with classic involvement of the skin and striated muscles. Following a prodromal period, patients develop a progressive proximal muscle weakness. Typical skin involvement includes heliotrope rash, facial erythema, Gottron's sign and nailfold capillary ...
H.-I. Huppertz, F. Dressler
openaire +3 more sources
Pediatric Annals, 2002
Juvenile dermatomyositis (JDM) is a multisystem disease characterized by acute and chronic lymphocytic inflammation of the skeletal muscle and skin. The disease is marked early in its course by the presence of a vasculopathy or vasculitis, and later by the development of calcinosis.
Maricarmen Lopez, Ann M. Reed
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Juvenile dermatomyositis (JDM) is a multisystem disease characterized by acute and chronic lymphocytic inflammation of the skeletal muscle and skin. The disease is marked early in its course by the presence of a vasculopathy or vasculitis, and later by the development of calcinosis.
Maricarmen Lopez, Ann M. Reed
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Autologous CD19‐Targeting CAR T Cells in a Patient With Refractory Juvenile Dermatomyositis
Arthritis & RheumatologyThe aim of this study is to report the safety and efficacy of CD19‐targeting chimeric antigen receptor (CAR) T cells in a child with refractory juvenile dermatomyositis (JDM).
R. Nicolai +15 more
semanticscholar +1 more source
Rheumatic Disease Clinics of North America, 1991
Juvenile dermatomyositis is a relatively rare, multisystem disease characterized by a nonsuppurative myositis which causes symmetrical weakness, rash and vasculitis; this last can affect the gastrointestinal tract and the myocardium. Late development of calcinosis is seen in approximately two thirds of patients.
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Juvenile dermatomyositis is a relatively rare, multisystem disease characterized by a nonsuppurative myositis which causes symmetrical weakness, rash and vasculitis; this last can affect the gastrointestinal tract and the myocardium. Late development of calcinosis is seen in approximately two thirds of patients.
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Juvenile Dermatomyositis: Advances in Pathogenesis, Assessment, and Management.
Current pediatric reviews, 2021BACKGROUND Juvenile dermatomyositis is the most common inflammatory myopathy in the pediatric age group and a major cause of mortality and morbidity in individuals with childhood rheumatic diseases.
A. Leung +4 more
semanticscholar +1 more source
Pediatric Clinics of North America, 1986
Myositis in childhood is characterized by elevated serum levels of muscle-derived enzymes, proximal symmetrical muscle weakness, abnormal EMG findings, and a muscle biopsy, which frequently documents an inflammatory process. In the pediatric age group, JDMS, which has characteristic cutaneous involvement in addition to myositis, is much more common ...
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Myositis in childhood is characterized by elevated serum levels of muscle-derived enzymes, proximal symmetrical muscle weakness, abnormal EMG findings, and a muscle biopsy, which frequently documents an inflammatory process. In the pediatric age group, JDMS, which has characteristic cutaneous involvement in addition to myositis, is much more common ...
openaire +3 more sources