Results 61 to 70 of about 7,339 (214)

Evaluation of anxiety, depression and quality of life using the hospital anxiety & depression scale and glaucoma quality of life-36 in juvenile open angle glaucoma patients [PDF]

, 2021
Introduction Glaucoma is the leading cause of blindness worldwide with a large number from Asia and Africa continents. Juvenile Open-Angle glaucoma is a rare subset of Primary open-angle glaucoma.
Rahman, Siti Khadijah Abdul
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Non‐RASopathy Genetic Syndromes Identified as the Molecular Cause of Disease in Patients Previously Diagnosed With Noonan Syndrome

American Journal of Medical Genetics Part A, Volume 200, Issue 3, Page 661-672, March 2026.
ABSTRACT Noonan Syndrome (NS) is a clinically and genetically heterogeneous condition characterized by typical facial dysmorphisms, short stature, congenital heart defects, and developmental delays. While variants in genes such as PTPN11, SOS1, and RAF1 account for most genetically confirmed cases, diagnosis is challenging due to phenotypic overlap ...
Gabriela Jeesoo Kim, Alexsandra Christianne Malaquias, Debora Romeo Bertola, Raissa Carneiro Rezende, Laurana De Polli Cellin, Lucas Vieira Lacerda Pires, Ana Maria Santillan‐Vasconez, Antônio Marcondes Lerario, Renata da Cunha Scalco, Alexander Augusto de Lima Jorge   +9 more
wiley   +1 more source

Profile of childhood glaucoma at a tertiary center in South India

Indian Journal of Ophthalmology, 2019
Purpose: To describe the prevalence of various types of childhood glaucomas, their clinical features and treatment methods. Methods: We prospectively included consecutive children with glaucoma presenting to glaucoma clinic for the first time between ...
Sirisha Senthil, Swathi Badakere, Jonnadula Ganesh, Rashmi Krishnamurthy, Siddharth Dikshit, Nikhil Choudhari, Chandrasekhar Garudadri, Anil K Mandal   +7 more
doaj   +1 more source

In vivo analysis of angle dysgenesis in primary congenital, juvenile, and adult-onset open angle glaucoma

, 2017
PURPOSE. The purpose of this study was to comparatively evaluate angle dysgenesis in vivo, among congenital, juvenile, and adult-onset open angle glaucoma patients. METHODS.
Viney Gupta, Abadh K. Chaurasia, Shikha Gupta, Bhavya Gorimanipalli, Gupta, A, Gorimanipalli, B, Amisha Gupta, Sharma, A, Gupta, V, Gupta, S, Ajay Sharma, Chaurasia, AK   +11 more
core   +1 more source

Nanostructured drug delivery systems for posterior segment eye diseases: Strategies to defy ocular barriers

BMEMat, Volume 4, Issue 1, March 2026.
Efficient drug delivery to the posterior segment of the eye has long been a challenging issue due to the complex ocular barriers. The review focuses on the promise held by nanoplatforms for barrier penetration and the key mechanisms involved, also highlighting their advantages in achieving efficient drug delivery and superior treatment of PSEDs ...
Yifan Shen, Ying Yao, Yan Zhang, Xinyu Shi, Ling Bai, Yang Zhong, Yan Zhang, Kun Zhang   +7 more
wiley   +1 more source

FOXC1 modulates MYOC secretion through regulation of the exocytic proteins RAB3GAP1, RAB3GAP2 and SNAP25.

PLoS ONE, 2017
The neurodegenerative disease glaucoma is one of the leading causes of blindness in the world. Glaucoma is characterized by progressive visual field loss caused by retinal ganglion cell (RGC) death.
Alexandra Rasnitsyn, Lance Doucette, Morteza Seifi, Tim Footz, Vincent Raymond, Michael A Walter   +5 more
doaj   +1 more source

Mydriasis as a Secondary Effect in Patients With HLA‐B27–Associated Uveitis

Medicine Advances, Volume 4, Issue 1, Page 12-19, March 2026.
HLA‐B27‐associated acute anterior uveitis causes significant inflammation of the iris and anterior chamber, which disrupts normal parasympathetic control and results in increased sympathetic tone leading to pupil dilation (mydriasis). This finding can sometimes resemble herpetic uveitis, making a clinical context and careful evaluation crucial for ...
Saim Mahmood Khan, Menahil Faheem Siddiqui, Syeda Areesha Shoaib, Surraiya Riaz Mahmood Khan, Jawairya Muhammad Hussain, Syeda Faiqa Batool, Hudda Amjad   +6 more
wiley   +1 more source

Choroidal Thickness in Juvenile Open Angle Glaucoma

Juvenile open angle glaucoma (JOAG) is an uncommon subtype of primary open angle glaucoma diagnosed between the ages of 3-40 years. It is believed to occur as a result of the immaturity of outflow pathways.
Sana Nadeem
core   +1 more source

A Novel Homozygous Nonsense Pathogenic Variant of the CPAMD8 Gene Associated With Congenital Microcoria

Clinical Genetics, Volume 109, Issue 3, Page 571-575, March 2026.
A novel CPAMD8 nonsense mutation c.2679C>G (p.Tyr893*) was identified in a patient with congenital microcoria, leading to reduced mRNA expression and predicted protein truncation. ABSTRACT Congenital microcoria (MCOR) is a rare inherited ocular disorder. Here, we describe a novel nonsense variant in the CPAMD8 gene in a patient with MCOR.
Jing‐Fan Gao, Xin Jin, Jing‐Rao Wang, Shu Wang, Hong Zhang   +4 more
wiley   +1 more source

An investigation of genetic risk factors in primary open-angle glaucoma

, 2009
Primary open-angle glaucoma (POAG) is a multifactorial disease with a strong genetic component. Notably however, few genes have been robustly associated with POAG in the general population.
Park, S.
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