Results 91 to 100 of about 29,187 (277)

SCOLIOSIS IN JUVENILE RHEUMATOID ARTHRITIS

, 1974
1. Eleven patients with juvenile rheumatoid arthritis, most of them young adults at a terminal stage, were found to have structural scoliosis with curves measuring between 20 and 80 degrees. 2.
J. J. Rombouts, C. Rombouts-Lindemans
core   +1 more source

Haemostatic changes and bleeding with anti‐IL‐6 directed therapy in autoimmune diseases

British Journal of Pharmacology, EarlyView.
Abstract Anti‐IL‐6 directed therapy, especially tocilizumab (TCZ), is widely used for the treatment of autoimmune diseases such as rheumatoid arthritis, giant cell arteritis and systemic juvenile idiopathic arthritis. Next to being a master regulator of inflammation, IL‐6 also is an important regulator of haemostasis. Although generally well tolerated,
Charlotte D. C. C. van der Heijden, Loes C. Oskam, Lenny van Bon, Chantal P. Rovers   +3 more
wiley   +1 more source

Dental age estimation in children affected by juvenile rheumatoid arthritis. [PDF]

Int J Legal Med, 2021
Pinchi V, Bianchi I, Pradella F, Vitale G, Focardi M, Tonni I, Ferrante L, Bucci A.   +7 more
europepmc   +1 more source

Long-term use of adalimumab in the treatment of rheumatic diseases

Open Access Rheumatology: Research and Reviews, 2009
Charalampos Papagoras, Paraskevi V Voulgari, Alexandros A DrososRheumatology Clinic, Department of Internal Medicine, Medical School, University of Ioannina, Ioannina, GreeceAbstract: Adalimumab, a fully humanized monoclonal antibody against ...
Charalampos Papagoras, Paraskevi V Voulgari, Alexandros A Drosos   +2 more
doaj  

Disseminated granuloma annulare: A cutaneous adverse effect of anti-TNF agents

Indian Journal of Dermatology, 2011
Tumor necrosis factor-alpha (TNF-α) inhibitors, such as etanercept, infliximab, and adalimumab, bind to TNF-α and thereby act as anti-inflammatory agents.
Mondhipa Ratnarathorn, Siba P Raychaudhuri, Stanley Naguwa   +2 more
doaj   +1 more source

A Phase 2 Trial of Frexalimab, a CD40L Antagonist, in Adolescents and Adults With Recent‐Onset Type 1 Diabetes (FABULINUS): Rationale and Study Design

Diabetes, Obesity and Metabolism, EarlyView.
ABSTRACT Introduction Type 1 diabetes (T1D) is a chronic autoimmune disease, characterised by progressive destruction of the insulin‐producing pancreatic β‐cells. Preserving remaining β‐cells at the time of diagnosis may improve long‐term outcomes. Frexalimab is a humanised monoclonal antibody specific for CD40L undergoing evaluation for treatment of ...
Andriy Cherkas, Baerbel Rotthaeuser, Niels Porksen, Pascale Labard, My‐Liên Nguyên‐Pascal, Mathieu Coudert, Baptiste Berthou, Marie Baccara‐Dinet, Gabor Boka, Mark Peakman, Felix Reschke, Michael J. Haller   +11 more
wiley   +1 more source

Negative-Pressure Pulmonary Edema After Difficult Endotracheal Intubation in a Patient with Juvenile Rheumatoid Arthritis Undergoing Spigelian Hernia Surgery: A Case Report. [PDF]

Am J Case Rep, 2022
Masui D, Fukahori S, Nakahara H, Tsuruhisa S, Sakamoto S, Higashidate N, Hashizume N, Koga Y, Saikusa N, Ishii S, Tanaka Y.   +10 more
europepmc   +1 more source

Australian clinical practice guideline: diagnosis and treatment of idiopathic multicentric Castleman disease

Internal Medicine Journal, EarlyView.
Abstract Idiopathic multicentric Castleman disease (iMCD) is a rare condition. The pathogenesis is incompletely understood; however, interleukin‐6 (IL‐6) is a major mediator. The clinical presentation is heterogeneous, from mild constitutional symptoms to severe multi‐organ failure.
Dipti Talaulikar, Jun Yen Ng, Adam Bryant, Annmarie Bosco, Hugh C. Caterson, Pratyush Giri, Pravin Hissaria, Simon J. Harrison, Stephen Lade, Connull Leslie, Jacinta Perram, H. Miles Prince, Dejan Radeski, Maureen Rischmueller, Craig Wallington‐Gates, Nicholas Weber, Alberta Hoi   +16 more
wiley   +1 more source

Sarilumab in Polyarticular-Course Juvenile Idiopathic Arthritis: Dose-Finding and 1-Year Analysis of a Phase 2b, Open-Label, Multicenter Study. [PDF]

Arthritis Care Res (Hoboken)
Objective This study assessed sarilumab in treating patients with polyarticular‐course juvenile idiopathic arthritis (pcJIA). Methods This phase 2b, open‐label study (NCT02776735) consisted of three sequential parts (each with a core‐treatment and extension phase).
De Benedetti F, Penadés IC, Nikishina I, Foeldvari I, Spindler AJ, Kozlova A, Rubio-Pérez N, Quartier P, Żuber Z, Barria R, Clemente D, Cornejo GV, Marzan K, Liu N, Xu C, DiMartino S, Giannelou A, Cao-Ghoul F, Akinlade B, Baret-Cormel L.   +19 more
europepmc   +2 more sources

Intra-articular corticosteroids in the treatment of juvenile idiopathic arthritis: Safety, efficacy, and features affecting outcome. A comprehensive review of the literature

Open Access Rheumatology: Research and Reviews, 2009
Alisa Carman GotteUniversity of Texas Southwestern Medical Center, Department of Pediatrics, Dallas, TX, USAAbstract: Intra-articular corticosteroid injection (IACI) has been used in the treatment of inflammatory arthritis in adults for over fifty years.
Alisa Carman Gotte
doaj