Biologic therapies are a major and growing driver of pharmaceutical expenditure globally, with tumor necrosis factor (TNF) inhibitors among the most widely used and costly biologics. In Australia, these therapies are funded through the Pharmaceutical Benefits Scheme (PBS), where biosimilars offer lower cost alternatives; however, the long‐term public ...
Chin Hang Yiu +4 more
wiley +1 more source
Changing Patterns of Hospitalisation and Orthopaedic Procedure Profiles in Major Inflammatory Rheumatic Diseases in Germany: a Nationwide Analysis of Hospital Discharge Data. [PDF]
Anees H +4 more
europepmc +1 more source
A Step‐by‐Step Guide to Successful Multiparametric Microbiota Flow Cytometry
Abstract The role of the human microbiota in host health is an important area of research. Conventional characterization of the complex microbial communities colonizing the human body is primarily performed using culture‐based or high‐throughput sequencing approaches, which have improved general understanding yet lack cellular features relevant for ...
Toni Sempert +5 more
wiley +1 more source
Case Report: Effectiveness of Abatacept for Palindromic Rheumatism Followed by Rheumatoid Factor-Positive Polyarticular Juvenile Idiopathic Arthritis. [PDF]
Fujita Y +4 more
europepmc +1 more source
Nailfold capillaroscopy is a non‐invasive imaging tool that can aid in the diagnosis and monitoring of juvenile myositis. Branched nailfold capillary morphology is more common in juvenile myositis patients, particularly those positive for TIF1γ+ autoantibodies. Juvenile myositis patients with more active disease demonstrate increased microhaemorrhages,
Nicholas McClellan +7 more
wiley +1 more source
Improving Lipid Screening Adherence in Inflammatory Arthritis Using a Two-Cycle Plan-Do-Study-Act (PDSA) Quality Improvement Intervention. [PDF]
Lilly M, Javed M, Jagannath D, Monga K.
europepmc +1 more source
Synthetic Food Colorants and Gut Microbiota: A Systematic Review of Preclinical Studies
ABSTRACT Growing evidence suggests that industrial food processing, including the excess consumption of food additives, might have a negative impact on human health. Despite regulatory safety evaluations, their impact on gut microbiota remains poorly characterized.
Sebastiano Alfio Torrisi +9 more
wiley +1 more source
Association of Childhood Acute Leukemia With Autoimmune Diseases
A possible link exists between various pediatric autoimmune diseases (AIDs) and increased risk of childhood leukemia. Although immune dysregulation is a key feature of these conditions, the connection between them remains unclear. In this study, using cancer registry data in Finland, the authors examined associations between AIDs and childhood acute ...
Ida Pellikka +4 more
wiley +1 more source
Multierosive Juvenile Idiopathic Arthritis With Positive Rheumatoid Factor: A Case Report of a Young Girl Followed at the University Clinics of Bukavu. [PDF]
Katabana DM +7 more
europepmc +1 more source
ABSTRACT Background and Aims Patients with Crohn's disease (CD) may experience suboptimal response to advanced therapies (ATs), including interleukin (IL)‐12/23 inhibitor ustekinumab and IL‐23 inhibitor risankizumab. In an evolving treatment landscape, this study evaluated indicators of suboptimal treatment with these agents. Methods This retrospective
Freddy Caldera +8 more
wiley +1 more source

